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Western Blot (WB) (RAB3A antibody validated by WB using 1. Human Cervical Cancer Cell Lysate (15ug) 2. Monkey Fibroblast Cell Lysate (15ug) 3. Human Cervical Cancer Cell transfected with mouse Rab3A-GFP (15ug) at 1:1000.)

Rabbit RAB3A Polyclonal Antibody | anti-RAB3A antibody

RAB3A antibody

Applications
Western Blot
Synonyms
RAB3A; Polyclonal Antibody; RAB3A antibody; Polyclonal RAB3A; Anti-RAB3A; RABA-3; RABA 3; member RAS oncogene family; anti-RAB3A antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Form/Format
Lyophilized powder. Add 100 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration
1 mg/ml (varies by lot)
Sequence Length
220
Applicable Applications for anti-RAB3A antibody
Western Blot (WB)
Application Notes
Optimal conditions to be determined by the end user
Biological Significance
RAB3A is involved in exocytosis by regulating a late step in synaptic vesicle fusion. It could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
Cross-Reactivity
Human, Mouse, Rat, Dog, Bovine, Pig, African Clawed Frog
Immunogen
RAB3A antibody was raised in rabbit using the C terminal of RAB3A as the immunogen
Preparation and Storage
Store at 4 degree C, following reconstitution, aliquot and store at -20 degree C. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(RAB3A antibody validated by WB using 1. Human Cervical Cancer Cell Lysate (15ug) 2. Monkey Fibroblast Cell Lysate (15ug) 3. Human Cervical Cancer Cell transfected with mouse Rab3A-GFP (15ug) at 1:1000.)

Western Blot (WB) (RAB3A antibody validated by WB using 1. Human Cervical Cancer Cell Lysate (15ug) 2. Monkey Fibroblast Cell Lysate (15ug) 3. Human Cervical Cancer Cell transfected with mouse Rab3A-GFP (15ug) at 1:1000.)
Related Product Information for anti-RAB3A antibody
Rabbit polyclonal RAB3A antibody
Product Categories/Family for anti-RAB3A antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,984 Da
NCBI Official Full Name
ras-related protein Rab-3A
NCBI Official Synonym Full Names
RAB3A, member RAS oncogene family
NCBI Official Symbol
RAB3A
NCBI Protein Information
ras-related protein Rab-3A
UniProt Protein Name
Ras-related protein Rab-3A
Protein Family
UniProt Gene Name
RAB3A
UniProt Entry Name
RAB3A_HUMAN

Uniprot Description

RAB3A: Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. Heterodimer with RIMS2. Part of a ternary complex involving PCLO and EPAC2. Interacts with RPH3A. Interacts with the exocyst complex through SEC15. Binds SYTL4, RIMS1 and RIMS2. Interacts with RAB3IP. Interacts with SGSM1 and SGSM3. Specifically expressed in brain. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein, monomeric, Rab; G protein; G protein, monomeric

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: synaptic vesicle; protein complex; secretory granule membrane; axon; plasma membrane; acrosome; terminal button; cytosol; endosome; vesicle

Molecular Function: GTPase activity; protein C-terminus binding; protein binding; ATPase activator activity; GTPase binding; GDP binding; GTP binding; myosin V binding; ATPase binding

Biological Process: mitochondrion organization and biogenesis; synaptic vesicle maturation; metabolic process; regulation of synaptic vesicle fusion to presynaptic membrane; neurotransmitter secretion; constitutive secretory pathway; protein secretion; regulation of short-term neuronal synaptic plasticity; post-embryonic development; intracellular protein transport; respiratory system process; synaptic transmission; synaptic vesicle exocytosis; glutamate secretion; axonogenesis; positive regulation of ATPase activity; sensory perception of touch; maintenance of presynaptic active zone structure; neuromuscular synaptic transmission; Rab protein signal transduction; response to electrical stimulus; vesicle docking during exocytosis; lung development; positive regulation of exocytosis

Research Articles on RAB3A

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Product Notes

The RAB3A rab3a (Catalog #AAA834219) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's RAB3A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Optimal conditions to be determined by the end user. Researchers should empirically determine the suitability of the RAB3A rab3a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAB3A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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