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Western Blot (WB) (Western blot analysis of KNTC1 expression in HEK293T (A) whole cell lysates.)

Rabbit anti-Human KNTC1 Polyclonal Antibody | anti-KNTC1 antibody

Anti-KNTC1 Antibody

Gene Names
KNTC1; ROD
Reactivity
Human
Applications
Western Blot
Purity
Purified by Immunogen Affinity Chromatography
Synonyms
KNTC1; Polyclonal Antibody; Anti-KNTC1 Antibody; KIAA0166; Kinetochore-associated protein 1; Rough deal homolog; HsROD; Rod; hRod; anti-KNTC1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of KNTC1 protein.
Purity/Purification
Purified by Immunogen Affinity Chromatography
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Applicable Applications for anti-KNTC1 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant fusion protein of human KNTC1. The exact sequence is proprietary.
Preparation and Storage
Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of KNTC1 expression in HEK293T (A) whole cell lysates.)

Western Blot (WB) (Western blot analysis of KNTC1 expression in HEK293T (A) whole cell lysates.)
Related Product Information for anti-KNTC1 antibody
Rabbit polyclonal antibody to KNTC1

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,102 Da
NCBI Official Full Name
kinetochore-associated protein 1
NCBI Official Synonym Full Names
kinetochore associated 1
NCBI Official Symbol
KNTC1
NCBI Official Synonym Symbols
ROD
NCBI Protein Information
kinetochore-associated protein 1
UniProt Protein Name
Kinetochore-associated protein 1
UniProt Gene Name
KNTC1
UniProt Synonym Gene Names
KIAA0166; HsROD; Rod; hRod

NCBI Description

This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. Experimental evidence indicated that the encoded protein functioned in a similar manner to that of the Drosophila rough deal protein. [provided by RefSeq, Jul 2008]

Uniprot Description

KNTC1: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores.

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: actin cytoskeleton; cytosol; kinetochore microtubule; nucleus; plasma membrane; spindle pole

Molecular Function: protein binding

Biological Process: cell division; mitotic cell cycle checkpoint; protein complex assembly; regulation of exit from mitosis; sister chromatid cohesion

Research Articles on KNTC1

Similar Products

Product Notes

The KNTC1 kntc1 (Catalog #AAA8307108) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-KNTC1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KNTC1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the KNTC1 kntc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KNTC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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