INPP1 recombinant protein

Recombinant Human INPP1 Protein

Cat. Num. AAA8249318

• Reactivity: Human
• Applications: ELISA, Western Blot, SDS-Page
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Synonyms: INPP1; Recombinant Human INPP1 Protein; Inositol polyphosphate 1-phosphatase; IPP; IPPase; INPP1 recombinant protein

• Host: Human cells
• Reactivity: Human
• Purity/Purification: Greater than 95% as determined by reducing SDS-PAGE.
• Form/Format: Lyophilized from a 0.2 muM filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
• Sequence: MSDILRELLC VSEKAANIAR ACRQQEALFQ LLIEEKKEGE KNKKFAVDFK TLADVLVQEV IKQNMENKFP GLEKNIFGEE SNEFTNDWGE KITLRLCSTE EETAELLSKV LNGNKVASEA LARVVHQDVA FTDPTLDSTE INVPQDILGI WVDPIDSTYQ YIKGSADIKS NQGIFPCGLQ CVTILIGVYD IQTGVPLMGV INQPFVSRDP NTLRWKGQCY WGLSYMGTNM HSLQLTISRR NGSETHTGNT GSEAAFSPSF SAVISTSEKE TIKAALSRVC GDRIFGAAGA GYKSLCVVQG LVDIYIFSED TTFKWDSCAA HAILRAMGGG IVDLKECLER NPETGLDLPQ LVYHVENEGA AGVDRWANKG GLIAYRSRKR LETFLSLLVQ NLAPAETHTV DHHHHHH
• Sequence Length: 399

• Applicable Applications for INPP1 recombinant protein: ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)
• Endotoxin: Less than 0.1 ng/mug (1 IEU/mug) as determined by LAL test.
• Directions for Use: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 mug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Preparation and Storage: Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.

Related Product Information for INPP1 recombinant protein

Recombinant Human INPP1 Protein is produced by our mammalian expression system and the target gene encoding Met1-Thr399 is expressed with a 6His tag at the C-terminus.

NCBI and Uniprot Product Information

• NCBI GI #: 193083155
• NCBI GeneID: 3628
• NCBI Accession #: NP_001122400.1
• NCBI GenBank Nucleotide #: NM_001128928.1
• UniProt Accession #: P49441
• Molecular Weight: 43,998 Da
• NCBI Official Full Name: inositol polyphosphate 1-phosphatase
• NCBI Official Synonym Full Names: inositol polyphosphate-1-phosphatase
• NCBI Official Symbol: INPP1
• NCBI Protein Information: inositol polyphosphate 1-phosphatase
• UniProt Protein Name: Inositol polyphosphate 1-phosphatase
• Protein Family: Inositol polyphosphate 1-phosphatase
• UniProt Gene Name: INPP1
• UniProt Synonym Gene Names: IPP; IPPase
• UniProt Entry Name: INPP_HUMAN

NCBI Description

This gene encodes the enzyme inositol polyphosphate-1-phosphatase, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 1 of the inositol ring from the polyphosphates inositol 1,4-bisphosphate and inositol 1,3,4-trisphophosphate. [provided by RefSeq, Jul 2008]

Uniprot Description

INPP1: the enzyme inositol polyphosphate-1-phosphatase, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 1 of the inositol ring from the polyphosphates inositol 1,4-bisphosphate and inositol 1,3,4-trisphophosphate. [provided by RefSeq, Jul 2008]

Protein type: Carbohydrate Metabolism - inositol phosphate; EC 3.1.3.57; Motility/polarity/chemotaxis; Phosphatase (non-protein)

Chromosomal Location of Human Ortholog: 2q32

Cellular Component: cytoplasm; cytosol

Molecular Function: inositol-1,4-bisphosphate 1-phosphatase activity; magnesium ion binding

Biological Process: inositol phosphate dephosphorylation; inositol phosphate metabolic process; phosphate metabolic process; signal transduction