Western Blot (WB)
(Western blot analysis of Clathrin Heavy Chain expression in Hela (A), MCF7 (B), mouse lung (C), rat brain (D) whole cell lysates.)
Rabbit Clathrin Heavy Chain Polyclonal Antibody | anti-CLTC antibody
Anti-Clathrin Heavy Chain Antibody
Western Blot (WB)
(Western blot analysis of Clathrin Heavy Chain expression in Hela (A), MCF7 (B), mouse lung (C), rat brain (D) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of Clathrin Heavy Chain expression in Hela (A), MCF7 (B), mouse lung (C), rat brain (D) whole cell lysates.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of Clathrin Heavy Chain staining in rat kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of Clathrin Heavy Chain staining in rat kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
NCBI and Uniprot Product Information
NCBI Description
Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. [provided by RefSeq, Jul 2008]
Uniprot Description
CLTC: a major protein component of the cytoplasmic face of coated vesicles and coated pits. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains.
Protein type: Vesicle; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 17q23.1
Cellular Component: clathrin-coated vesicle; cytosol; focal adhesion; intracellular membrane-bound organelle; membrane; plasma membrane; protein complex; spindle; trans-Golgi network membrane
Molecular Function: clathrin light chain binding; double-stranded RNA binding; protein binding; protein kinase binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; mitosis; osteoblast differentiation; receptor internalization; receptor-mediated endocytosis; retrograde transport, endosome to Golgi; transferrin transport; Wnt receptor signaling pathway, planar cell polarity pathway
Research Articles on CLTC
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Product Notes
The CLTC cltc (Catalog #AAA8247323) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Clathrin Heavy Chain Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Clathrin Heavy Chain can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1/500 - 1/2000; IHC: 1/50 - 1/100. Researchers should empirically determine the suitability of the CLTC cltc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Clathrin Heavy Chain, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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