Immunohistochemistry (IHC)
(Immunochemical staining of human TNRC6B in human brain with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human TNRC6B Polyclonal Antibody | anti-TNRC6B antibody
Anti-TNRC6B Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
TNRC6B; Polyclonal Antibody; Anti-TNRC6B Antibody; Rabbit Polyclonal; TNRC6B Antibody; Rabbit PAb; Antigen Affinity Purified; Anti-RP5-1042K10.7 Antibody; anti-TNRC6B antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human TNRC6B
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-TNRC6B antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:50-1:200
Immunogen
E Coli-derived Human TNRC6B fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human TNRC6B fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human TNRC6B in human brain with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human TNRC6B in human brain with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-TNRC6B antibody
TNRC6B (Trinucleotide Repeat Containing Adaptor 6B) is a Protein Coding gene. The TNRC6B gene, located on 22q13.1, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. TNRC6B encodes a protein important for RNA silencing. TNRC6B plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). TNRC6B is widely expressed in the testis, thyroid, and other tissues. Diseases associated with TNRC6B include Epilepsy, Familial Temporal Lobe, 5, and Generalized Epilepsy With Febrile Seizures Plus, Type 7. Among its related pathways are RET signaling and Signaling by GPCR. 197 organisms have orthologs with the human gene TNRC6B.
References
Sun J, et al. (2009) Sequence variants at 22q13 are associated with prostate cancer risk. Cancer Res 69 (1): 10-15.Granadillo JL, et al. (2020) Pathogenic variants in tnrc6b cause a genetic disorder characterised by developmental delay/intellectual disability and a spectrum of neurobehavioural phenotypes including autism and adhd. J Med Genet 57 (10): 717-724.Bondagji NS, et al. (2017) Replication of gwas loci revealed the moderate effect of tnrc6b locus on susceptibility of saudi women to develop uterine leiomyomas. J Obstet Gynaecol Res 43 (2): 330-338.
Similar Products
Product Notes
The TNRC6B (Catalog #AAA8109793) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TNRC6B Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TNRC6B can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the TNRC6B for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNRC6B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
