Immunohistochemistry (IHC)
(Immunochemical staining of human MSRA in human kidney with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human MSRA Polyclonal Antibody | anti-MSRA antibody
Anti-MSRA Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
MSRA; Polyclonal Antibody; Anti-MSRA Antibody; Rabbit Polyclonal; MSRA/Methionine Mulfoxide Reductase A Antibody; Rabbit PAb; Antigen Affinity Purified; methionine sulfoxide reductase A; Anti-PMSR Antibody; anti-MSRA antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human MSRA/Methionine Mulfoxide Reductase A
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-MSRA antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:100-1:400
Immunogen
E Coli-derived Human MSRA/Methionine Mulfoxide Reductase A fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human MSRA/Methionine Mulfoxide Reductase A fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human MSRA in human kidney with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human MSRA in human kidney with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human MSRA in human colon with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human MSRA in human colon with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-MSRA antibody
MSRA (Methionine Sulfoxide Reductase A) is a Protein Coding gene. The MSRA gene, located on 8p23.1, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat, etc. MSRA belongs to the MsrA Met sulfoxide reductase family. MsrA is a potent intracellular oxidoreductase and serves as an essential factor that protects cells against oxidative damage. However, the therapeutic use of exogenous MsrA in oxidative stress-induced diseases is limited, because it cannot enter the cells. Considerable evidence indicates a role for MsrA in lens cell resistance to oxidative stress through its maintenance of mitochondrial function. Correspondingly, increased protein methionine sulfoxide (PMSO) is associated with lens aging and human cataract formation, suggesting that loss of MsrA activity is associated with this disease.
References
Wu Y, et al. (2015) Pep-1-msra ameliorates inflammation and reduces atherosclerosis in apolipoprotein e deficient mice. J Transl Med 13 316.Tarafdar S, et al. (2019) Drosophila methionine sulfoxide reductase a (msra) lacks methionine oxidase activity. Free Radic Biol Med 131 154-161.Fu X, et al. (2017) Methionine sulfoxide reductase a (msra) and its function in ubiquitin-like protein modification in archaea. mBio 8 (5): e01169-17.Brennan LA, et al. (2009) Deletion of mouse msra results in hbo-induced cataract: Msra repairs mitochondrial cytochrome c. Mol Vis 15 985-999.
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Product Notes
The MSRA (Catalog #AAA8108636) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MSRA Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MSRA can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:100-1:400. Researchers should empirically determine the suitability of the MSRA for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MSRA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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