Mouse anti-Human COQ7 Monoclonal Antibody | anti-COQ7 antibody
Anti-COQ7 Antibody, Mouse Monoclonal
Gene Names
COQ7; CAT5; CLK1; CLK-1
Reactivity
Human
Applications
ELISA
Purity
Protein A
Synonyms
COQ7; Monoclonal Antibody; Anti-COQ7 Antibody; Mouse Monoclonal; COQ7 Antibody; Mouse MAb; coenzyme Q7 homolog; ubiquinone (yeast); Anti-CAT5 Antibody; Anti-CLK-1 Antibody; Anti-CLK1 Antibody; anti-COQ7 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone Number
06
Specificity
Human COQ7
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-COQ7 antibody
ELISA (EIA) (Cap)
Application Notes
ELISA (Cap): This antibody will detect Human COQ7 in ELISA pair set.
In a sandwich ELISA, it can be used as capture antibody.
In a sandwich ELISA, it can be used as capture antibody.
Immunogen
Recombinant Human COQ7 Protein
Conjugation
Unconjugated
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human COQ7 (rh COQ7). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-COQ7 antibody
Ubiquinone biosynthesis protein COQ7 homolog, also known as Coenzyme Q biosynthesis protein 7 homolog, Timing protein clk-1 homolog and COQ7, is a mitochondrion inner membrane and peripheral membrane protein which belongs to theCOQ7 family. It is expressed dominantly in heart and skeletal muscle. COQ7 is synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. This enzyme is responsible for the hydroxylation of 5-demethoxyubiquinone to 5-hydroxyubiquinone. Human COQ7 protein is mostly helical, and contains an alpha-helical membrane insertion. It has a potential N-glycosylation site, a phosphorylation site for protein kinase C and another for casein kinase II, and three N-myristoylation sites. COQ7 is involved in lifespan determination in ubiquinone-independent manner. It is also involved in ubiquinone biosynthesis. COQ7 is potential central metabolic regulator.
References
Ewbank J.J., et al., 1997, Science. 275: 980-3. Vajo Z., et al., 1999, Mamm. Genome. 10: 1000-4. Wiemann S., et al., 2001, Genome Res. 11: 422-35. Stenmark, P. et al., 2001, J Biol Chem. 276 (36): 33297-300. Martin J., et al., 2004, Nature. 432: 988-94.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
217
NCBI Official Full Name
Ubiquinone biosynthesis protein COQ7 homolog
NCBI Official Synonym Full Names
coenzyme Q7 homolog, ubiquinone (yeast)
NCBI Official Symbol
COQ7
NCBI Official Synonym Symbols
CAT5; CLK1; CLK-1
NCBI Protein Information
ubiquinone biosynthesis protein COQ7 homolog; placental protein KG-20; timing protein clk-1 homolog; COQ7 coenzyme Q, 7 homolog ubiquinone; coenzyme Q biosynthesis protein 7 homolog
UniProt Protein Name
Ubiquinone biosynthesis protein COQ7 homolog
Protein Family
UniProt Gene Name
COQ7
UniProt Entry Name
COQ7_HUMAN
NCBI Description
The protein encoded by this gene is similar to a mitochondrial di-iron containing hydroxylase in Saccharomyces cerevisiae that is involved with ubiquinone biosynthesis. Mutations in the yeast gene lead to slower development and longer life span. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
Uniprot Description
COQ7: Involved in lifespan determination in ubiquinone- independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator. Belongs to the COQ7 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cofactor and Vitamin Metabolism - ubiquinone and other terpenoid-quinone biosynthesis; Mitochondrial
Chromosomal Location of Human Ortholog: 16p12.3
Cellular Component: mitochondrial inner membrane; nucleus
Molecular Function: metal ion binding
Biological Process: ubiquinone biosynthetic process; neurogenesis; in utero embryonic development; determination of adult life span; neural tube formation; age-dependent response to oxidative stress; organelle ATP synthesis coupled electron transport
Research Articles on COQ7
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Product Notes
The COQ7 coq7 (Catalog #AAA8106269) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-COQ7 Antibody, Mouse Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's COQ7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA) (Cap). ELISA (Cap): This antibody will detect Human COQ7 in ELISA pair set. In a sandwich ELISA, it can be used as capture antibody. Researchers should empirically determine the suitability of the COQ7 coq7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COQ7, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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