Western Blot (WB)
(human placenta tissue were subjected to SDS PAGE followed by western blot with MBS769295 (FCGRT-Specific antibody) at dilution of 1:300)
Rabbit anti-Human FcRn Polyclonal Antibody | anti-FcRn antibody
FcRn-Specific Rabbit Polyclonal
Reactivity
Human
Applications
ELISA, Western Blot
Purity
>=95% as determined by SDS-PAGEImmunogen Affinity Purified
Synonyms
FcRn; Polyclonal Antibody; FcRn-Specific Rabbit Polyclonal; Alpha chain; FCGRT; FCRN; Neonatal Fc receptor; anti-FcRn antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human; other species are not tested.
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
88
Applicable Applications for anti-FcRn antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:200-1:1000
Immunogen
Fc fragment of IgG, receptor, transporter, alpha
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Western Blot (WB)
(human placenta tissue were subjected to SDS PAGE followed by western blot with MBS769295 (FCGRT-Specific antibody) at dilution of 1:300)
Western Blot (WB)
(human placenta tissue were subjected to SDS PAGE followed by western blot with MBS769295 (FCGRT-Specific antibody) at dilution of 1:300)
Related Product Information for anti-FcRn antibody
The neonatal Fc receptor for IgG (FcRn) is a membrane-associated receptor which acts as a key determinant of IgG homeostasis. FcRn is similar in structure to major histocompatibility class I molecules. It is a heterodimer composed of a alpha chain associated with Beta2-microglobulin. FcRn transfers IgG from the mother to the fetus across the placenta and the proximal small intestine. In addition, throughout life, FcRn protects IgG from degradation and thus regulates the serum half-life of IgG (PMID: 17703228)
NCBI and Uniprot Product Information
Uniprot Description
FCGRT: Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus. Belongs to the immunoglobulin superfamily.
Protein type: Immunoglobulin superfamily; Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 19q13.3
Cellular Component: plasma membrane
Molecular Function: antigen binding; beta-2-microglobulin binding; IgG binding; IgG receptor activity; peptide antigen binding
Biological Process: antigen processing and presentation
Similar Products
Product Notes
The FcRn (Catalog #AAA769295) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FcRn-Specific Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FcRn can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:200-1:1000. Researchers should empirically determine the suitability of the FcRn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FcRn, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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