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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human kidney cancer tissue slide using MBS7607723 (CASP9 antibody) at dilution of 1:200)

Rabbit anti-Human CASP9 Polyclonal Antibody | anti-CASP9 antibody

Anti-CASP9 Antibody

Gene Names
Casp9; Mch6; APAF-3; CASP-9; AI115399; AW493809; ICE-LAP6; Caspase-9
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
>=95% as determined by SDS-PAGE
Immunogen affinity purified
Synonyms
CASP9; Polyclonal Antibody; Anti-CASP9 Antibody; APAF 3; APAF3; Apoptotic protease Mch 6; CASP 9; Caspase 9; CASPASE 9c; Caspase9; Caspase-9; ICE LAP6; ICE like apoptotic protease 6; MCH6; anti-CASP9 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen affinity purified
Form/Format
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Sequence Length
454
Applicable Applications for anti-CASP9 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:500
Immunogen
Caspase-9
Preparation and Storage
Store at -20 degree C for 24 months. Avoid repeated freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney cancer tissue slide using MBS7607723 (CASP9 antibody) at dilution of 1:200)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human kidney cancer tissue slide using MBS7607723 (CASP9 antibody) at dilution of 1:200)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed MW: 49kDa
NCBI Official Full Name
caspase-9 isoform 1
NCBI Official Synonym Full Names
caspase 9
NCBI Official Symbol
Casp9
NCBI Official Synonym Symbols
Mch6; APAF-3; CASP-9; AI115399; AW493809; ICE-LAP6; Caspase-9
NCBI Protein Information
caspase-9
UniProt Protein Name
Caspase-9
Protein Family
UniProt Gene Name
Casp9
UniProt Synonym Gene Names
Mch6; CASP-9; APAF-3; ICE-LAP6

NCBI Description

This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, the initiator caspase, is activated after cytochrome c release from mitochondria and targets downstream effectors. In mouse, deficiency of this gene can cause perinatal lethality. This protein may have a role in normal brain development. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Apr 2013]

Uniprot Description

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) ().

Research Articles on CASP9

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Product Notes

The CASP9 casp9 (Catalog #AAA7607723) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CASP9 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CASP9 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:50-1:500. Researchers should empirically determine the suitability of the CASP9 casp9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CASP9, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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