Monkey Collagenase, Type II ELISA Kit | Collagenase II elisa kit

Monkey Collagenase, Type II ELISA Kit

Cat. Num. AAA749405

• Reactivity: Monkey
• Synonyms: Collagenase; Type II; Monkey Collagenase; Type II ELISA Kit; Collagenase II elisa kit

• Reactivity: Monkey

• Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
• Preparation and Storage: Store all reagents at 2-8 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 203499
• NCBI GeneID: 171052
• Molecular Weight: 53,375 Da
• NCBI Official Full Name: collagenase, partial
• NCBI Official Synonym Full Names: matrix metallopeptidase 13
• NCBI Official Symbol: Mmp13
• NCBI Protein Information: collagenase 3; MMP-13; UMRCASE; collagenase-3; matrix metalloproteinase 13; matrix metalloproteinase-13
• UniProt Protein Name: Collagenase 3
• UniProt Gene Name: Mmp13
• UniProt Synonym Gene Names: MMP-13
• UniProt Entry Name: MMP13_RAT

NCBI Description

enzyme that degrades collagen type I [RGD, Feb 2006]

Uniprot Description

Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion ().