Goat Ubiquitin fold Modifier 1 (UFM1) ELISA Kit | UFM1 elisa kit

Goat Ubiquitin Fold Modifier 1 (UFM1) ELISA Kit

Cat. Num. AAA7260309

• Gene Names: UFM1; HLD14; BM-002; C13orf20
• Reactivity: Goat
• Synonyms: Ubiquitin fold Modifier 1 (UFM1); Goat Ubiquitin Fold Modifier 1 (UFM1) ELISA Kit; UFM1 elisa kit

• Reactivity: Goat
• Sequence Length: 85

• Reproducibility: Intra-Assay: CV<10%; Inter-Assay: CV<15%
• Reactivity Note: No significant cross-reactivity or interference between this antigen and analogues was observed. NOTE: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection, therefore, cross reaction may still exist in some cases.
• Preparation and Storage: Store at 2-8 degree C.; The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.

Related Product Information for UFM1 elisa kit

This ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of the targets.

Product Categories/Family for UFM1 elisa kit

Cell Biology

NCBI and Uniprot Product Information

• NCBI GI #: 7705300
• NCBI GeneID: 51569
• NCBI Accession #: NP_057701.1
• NCBI GenBank Nucleotide #: NM_016617.4
• UniProt Accession #: P61960; Q14346; Q5VXS0; Q6IAG6; Q9CPX2; Q9NZF2
• Molecular Weight: 10,960 Da
• NCBI Official Full Name: ubiquitin-fold modifier 1 isoform 1
• NCBI Official Synonym Full Names: ubiquitin fold modifier 1
• NCBI Official Symbol: UFM1
• NCBI Official Synonym Symbols: HLD14; BM-002; C13orf20
• NCBI Protein Information: ubiquitin-fold modifier 1
• UniProt Protein Name: Ubiquitin-fold modifier 1
• UniProt Gene Name: UFM1
• UniProt Synonym Gene Names: C13orf20

NCBI Description

UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 (UBE1DC1; MIM 610552) and E2-like conjugating enzyme UFC1 (MIM 610554) in a manner analogous to ubiquitylation (see UBE2M; MIM 603173) (Komatsu et al., 2004 [PubMed 15071506]).[supplied by OMIM, Dec 2008]

Uniprot Description

Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer (PubMed:15071506, PubMed:20018847). The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 (PubMed:15071506, PubMed:20018847). This post-translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes (PubMed:15071506, PubMed:20018847). TRIP4 ufmylation may for instance play a role in nuclear receptors-mediated transcription (PubMed:25219498). Other substrates may include DDRGK1 with which it may play a role in the cellular response to endoplasmic reticulum stress (Probable).