Western Blot (WB)
(All lanes: O-phosphoseryl-tRNA(Sec) selenium transferase antibody at 2ug/ml+293T whole cell lysate)
Rabbit anti-Human O-phosphoseryl-tRNA(Sec) selenium transferase Polyclonal Antibody | anti-SEPSECS antibody
O-phosphoseryl-tRNA(Sec) selenium transferase Polyclonal Antibody
Gene Names
SEPSECS; LP; SLA; PCH2D; SLA/LP
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Synonyms
O-phosphoseryl-tRNA(Sec) selenium transferase; Polyclonal Antibody; O-phosphoseryl-tRNA(Sec) selenium transferase Polyclonal Antibody; Aldehyde dehydrogenase family 1 member A2; Retinaldehyde-specific dehydrogenase type 2; ALDH1A2; RALDH2; anti-SEPSECS antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total O-phosphoseryl-tRNA(Sec) selenium transferase polyclonal antibody.
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
501
Applicable Applications for anti-SEPSECS antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western Blot: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200
Immunohistochemistry: 1:20 - 1:200
Immunogen
Recombinant Human O-phosphoseryl-tRNA(Sec) selenium transferase protein
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C
Western Blot (WB)
(All lanes: O-phosphoseryl-tRNA(Sec) selenium transferase antibody at 2ug/ml+293T whole cell lysate)
Western Blot (WB)
(All lanes: O-phosphoseryl-tRNA(Sec) selenium transferase antibody at 2ug/ml+293T whole cell lysate)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embeded human kidney using at dilution of 1:100.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embeded human kidney using at dilution of 1:100.)
Related Product Information for anti-SEPSECS antibody
Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently
Product Categories/Family for anti-SEPSECS antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,411 Da
NCBI Official Full Name
O-phosphoseryl-tRNA(Sec) selenium transferase
NCBI Official Synonym Full Names
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
NCBI Official Symbol
SEPSECS
NCBI Official Synonym Symbols
LP; SLA; PCH2D; SLA/LP
NCBI Protein Information
O-phosphoseryl-tRNA(Sec) selenium transferase
UniProt Protein Name
O-phosphoseryl-tRNA(Sec) selenium transferase
Protein Family
UniProt Gene Name
SEPSECS
UniProt Synonym Gene Names
TRNP48; LP; Sec synthase; SepSecS; SLA
UniProt Entry Name
SPCS_HUMAN
Uniprot Description
SLA/LP: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. Defects in SEPSECS are the cause of pontocerebellar hypoplasia type 2D (PCH2D). PCH2D is a disorder characterized by postnatal onset of progressive atrophy of the cerebrum and cerebellum, microcephaly, profound mental retardation, spasticity, and variable seizures. Belongs to the SepSecS family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.9.1.2; RNA-binding; Transferase
Chromosomal Location of Human Ortholog: 4p15.2
Cellular Component: cytoplasm; cytosol; nucleus
Molecular Function: protein binding; tRNA binding
Biological Process: selenocysteine incorporation; selenocysteine metabolic process
Disease: Pontocerebellar Hypoplasia, Type 2d
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Product Notes
The SEPSECS sepsecs (Catalog #AAA9415907) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The O-phosphoseryl-tRNA(Sec) selenium transferase Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's O-phosphoseryl-tRNA(Sec) selenium transferase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:500 - 1:1000 Immunohistochemistry: 1:20 - 1:200. Researchers should empirically determine the suitability of the SEPSECS sepsecs for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "O-phosphoseryl-tRNA(Sec) selenium transferase, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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