Canine Cyclin-related protein FAM58A (FAM58A) ELISA Kit | FAM58A elisa kit
Canine Cyclin-related protein FAM58A (FAM58A) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin-box-fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Uniprot Description
FAM58B: May have a role in cell proliferation. Defects in FAM58A are the cause of toe syndactyly, telecanthus, and anogenital and renal malformations (STAR); also known as STAR syndrome or syndactyly with renal and anogenital malformations. Belongs to the cyclin family. Cyclin-like FAM58 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: Xq28
Cellular Component: DNA-directed RNA polymerase II, holoenzyme
Molecular Function: protein binding; protein kinase activator activity; protein kinase binding
Biological Process: regulation of transcription, DNA-dependent; positive regulation of MAPKKK cascade; positive regulation of protein kinase activity; regulation of cyclin-dependent protein kinase activity
Disease: Toe Syndactyly, Telecanthus, And Anogenital And Renal Malformations
Research Articles on FAM58A
Similar Products
Product Notes
The Canine FAM58A fam58a (Catalog #AAA7253265) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7253265 ELISA Kit recognizes Canine FAM58A. It is sometimes possible for the material contained within the vial of "Cyclin-related protein FAM58A (FAM58A), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
