Human AT rich interactive domain containing protein 4B (ARID4B) ELISA Kit | ARID4B elisa kit

Human AT rich interactive domain containing protein 4B (ARID4B) ELISA Kit

Cat. Num. AAA7228937

• Gene Names: ARID4B; BCAA; BRCAA1; RBP1L1; SAP180; RBBP1L1
• Reactivity: Human
• Synonyms: AT rich interactive domain containing protein 4B (ARID4B); Human AT rich interactive domain containing protein 4B (ARID4B) ELISA Kit; ARID4B elisa kit

• Reactivity: Human

• Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
• Assay Type: Competitive
• Detection Range: 10-250ng/mL
• Sensitivity: 1.0ng/mL
• Preparation and Storage: Store all reagents at 2-8 degree C.

Product Categories/Family for ARID4B elisa kit

Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

• NCBI GI #: 143955276
• NCBI GeneID: 51742
• Molecular Weight: 91,140 Da
• NCBI Official Full Name: AT-rich interactive domain-containing protein 4B
• NCBI Official Synonym Full Names: AT rich interactive domain 4B (RBP1-like)
• NCBI Official Symbol: ARID4B
• NCBI Official Synonym Symbols: BCAA; BRCAA1; RBP1L1; SAP180; RBBP1L1
• NCBI Protein Information: AT-rich interactive domain-containing protein 4B; Rb-binding protein homolog; SIN3A-associated protein 180; sin3-associated polypeptide p180; ARID domain-containing protein 4B; breast cancer-associated antigen 1; 180 kDa Sin3-associated polypeptide; breast carcinoma-associated antigen; breast cancer-associated antigen BRCAA1; retinoblastoma-binding protein 1-like 1; histone deacetylase complex subunit SAP180
• UniProt Protein Name: AT-rich interactive domain-containing protein 4B
• Protein Family: AT-rich interactive domain-containing protein
• UniProt Gene Name: ARID4B
• UniProt Synonym Gene Names: BRCAA1; RBBP1L1; RBP1L1; SAP180; ARID domain-containing protein 4B; Sin3-associated polypeptide p180
• UniProt Entry Name: ARI4B_HUMAN

NCBI Description

This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]

Uniprot Description

ARID4B: Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 1q42.3

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: protein binding

Biological Process: regulation of transcription from RNA polymerase II promoter; establishment and/or maintenance of chromatin architecture; genetic imprinting; transcription, DNA-dependent; negative regulation of gene expression, epigenetic; positive regulation of transcription from RNA polymerase II promoter; gene expression; spermatogenesis; regulation of gene expression, epigenetic