Porcine Cytotoxic and regulatory T-cell molecule (CRTAM) ELISA Kit | CRTAM elisa kit
Porcine Cytotoxic and regulatory T-cell molecule (CRTAM) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al., 2008 [PubMed 18329370]).[supplied by OMIM, Feb 2009]
Uniprot Description
CRTAM: Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. Belongs to the nectin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Apoptosis; Membrane protein, integral
Chromosomal Location of Human Ortholog: 11q24.1
Cellular Component: integral to membrane; plasma membrane
Molecular Function: receptor binding
Biological Process: regulation of immune response; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; detection of tumor cell; activated T cell proliferation; detection of stimulus; cell recognition; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of cytokine secretion; T cell mediated cytotoxicity
Research Articles on CRTAM
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Product Notes
The Porcine CRTAM crtam (Catalog #AAA7223877) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7223877 ELISA Kit recognizes Porcine CRTAM. It is sometimes possible for the material contained within the vial of "Cytotoxic and regulatory T-cell molecule (CRTAM), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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