Canine AP-1 complex subunit mu-1 (AP1M1) ELISA Kit | AP1M1 elisa kit

Canine AP-1 complex subunit mu-1 (AP1M1) ELISA Kit

Cat. Num. AAA7209377

• Gene Names: AP1M1; AP47; CLTNM; MU-1A; CLAPM2
• Reactivity: Canine
• Synonyms: AP-1 complex subunit mu-1 (AP1M1); Canine AP-1 complex subunit mu-1 (AP1M1) ELISA Kit; AP1M1 elisa kit

• Reactivity: Canine

• Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
• Assay Type: Competitive
• Detection Range: 0.5-10ng/mL
• Sensitivity: 0.1ng/mL
• Preparation and Storage: Store all reagents at 2-8 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 14210504
• NCBI GeneID: 8907
• NCBI Accession #: NP_115882.1
• NCBI GenBank Nucleotide #: NM_032493.3
• Molecular Weight: 49,840 Da
• NCBI Official Full Name: AP-1 complex subunit mu-1 isoform 2
• NCBI Official Synonym Full Names: adaptor-related protein complex 1, mu 1 subunit
• NCBI Official Symbol: AP1M1
• NCBI Official Synonym Symbols: AP47; CLTNM; MU-1A; CLAPM2
• NCBI Protein Information: AP-1 complex subunit mu-1; mu-adaptin 1; mu1A-adaptin; HA1 47 kDa subunit; clathrin adaptor protein AP47; AP-mu chain family member mu1A; golgi adaptor AP-1 47 kDa protein; clathrin coat assembly protein AP47; clathrin coat-associated protein AP47; adaptor protein complex AP-1 mu-1 subunit; adaptor protein complex AP-1 subunit mu-1; golgi adaptor HA1/AP1 adaptin mu-1 subunit; adapter-related protein complex 1 subunit mu-1; adaptor-related protein complex 1 mu-1 subunit; adaptor-related protein complex 1 subunit mu-1; clathrin assembly protein complex 1, medium chain; clathrin assembly protein complex AP1, mu subunit; clathrin assembly protein complex 1 medium chain 1; clathrin assembly protein complex 1 mu-1 medium chain 1
• UniProt Protein Name: AP-1 complex subunit mu-1
• Protein Family: AP-1 complex
• UniProt Gene Name: AP1M1
• UniProt Synonym Gene Names: CLTNM
• UniProt Entry Name: AP1M1_HUMAN

NCBI Description

The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

AP1M1: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Belongs to the adaptor complexes medium subunit family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 19p13.12

Cellular Component: Golgi membrane; clathrin adaptor complex; cytoplasmic vesicle membrane; membrane; lysosomal membrane; clathrin coated vesicle membrane; trans-Golgi network membrane; cytosol

Molecular Function: protein binding

Biological Process: intracellular protein transport; viral reproduction; melanosome organization and biogenesis; antigen processing and presentation of exogenous peptide antigen via MHC class II; post-Golgi vesicle-mediated transport; regulation of defense response to virus by virus