Guinea Pig Bromodomain-containing protein 3 (BRD3) ELISA Kit | BRD3 elisa kit
Guinea pig Bromodomain-containing protein 3 (BRD3) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known. [provided by RefSeq, Jul 2008]
Uniprot Description
BRD3: Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets. Regulates transcription of the CCND1 gene. A chromosomal aberration involving BRD3 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with NUT which produces a BRD3-NUT fusion protein. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, atypical; ATYPICAL group; BRD family
Chromosomal Location of Human Ortholog: 9q34
Cellular Component: nucleus
Molecular Function: protein binding; chromatin binding
Biological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; chromatin modification
Research Articles on BRD3
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Product Notes
The Guinea Pig BRD3 brd3 (Catalog #AAA7206334) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7206334 ELISA Kit recognizes Guinea Pig BRD3. It is sometimes possible for the material contained within the vial of "Bromodomain-containing protein 3 (BRD3), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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