Rabbit US12 Polyclonal Antibody | anti-US12 antibody
Rabbit anti-Human herpesvirus 1 (strain 17)(HHV-1)(Human herpes simplex virus 1) US12 Polyclonal Antibody
Reactivity
Human herpesvirus 1
Applications
ELISA, Western Blot
Purity
Protein A/G
Synonyms
US12; Polyclonal Antibody; Rabbit anti-Human herpesvirus 1 (strain 17)(HHV-1)(Human herpes simplex virus 1) US12 Polyclonal Antibody; US12 Antibody; ICP47 protein; Immediate-early protein IE12; Immediate-early-5; Infected cell protein 47; US12 protein; Vmw12); anti-US12 antibody
Host
Rabbit
Reactivity
Human herpesvirus 1
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Protein A/G
Form/Format
Liquid
Applicable Applications for anti-US12 antibody
ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
Immunogen
Recombinant Human herpesvirus 1 US12 protein
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH7.4
Constituents: 50% Glycerol, 0.01M PBS, pH7.4
Conjugation
Non-conjugate
Modification
Unmodified
Immunogen Species
Human herpesvirus 1 (strain 17)(HHV-1)(Human herpes simplex virus 1)
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
TAP transporter inhibitor ICP47
NCBI Official Symbol
US12
NCBI Protein Information
inhibits antigen presentation; involved in immune regulation
UniProt Protein Name
ICP47 protein
Protein Family
UniProt Gene Name
US12
UniProt Entry Name
ICP47_HHV11
Uniprot Description
Plays a role in the inhibition of host immune response. Binds specifically to transporters associated with antigen processing (TAP), thereby blocking peptide-binding and translocation by TAP as well as subsequent loading of peptides onto MHC class I molecules. Empty MHC I molecules are retained in the endoplasmic reticulum and ultimately directed to proteasomal degradation. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes.
Research Articles on US12
Similar Products
Product Notes
The US12 us12 (Catalog #AAA7164254) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-Human herpesvirus 1 (strain 17)(HHV-1)(Human herpes simplex virus 1) US12 Polyclonal Antibody reacts with Human herpesvirus 1 and may cross-react with other species as described in the data sheet. AAA Biotech's US12 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), WB (Western Blot) (ensure identification of antigen). Researchers should empirically determine the suitability of the US12 us12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "US12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
