Rabbit anti-Human ATP6V1D Polyclonal Antibody | anti-ATP6V1D antibody

ATP6V1D Antibody, FITC Conjugated

Cat. Num. AAA7134533

• Gene Names: ATP6V1D; VATD; VMA8; ATP6M
• Reactivity: Human
• Applications: ELISA
• Purity: >95%, Protein G Purified
• Synonyms: ATP6V1D; Polyclonal Antibody; ATP6V1D Antibody; FITC Conjugated; V-type proton ATPase subunit D (V-ATPase subunit D) (V-ATPase 28 kDa accessory protein) (Vacuolar proton pump subunit D); ATP6M VATD; anti-ATP6V1D antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G Purified
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

• Applicable Applications for anti-ATP6V1D antibody: ELISA (EIA)
• Immunogen: Recombinant Human V-type proton ATPase subunit D protein (1-247AA)
• Immunogen Species: Human
• Conjugate: FITC
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Product Categories/Family for anti-ATP6V1D antibody

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 10720351
• NCBI GeneID: 51382
• UniProt Accession #: Q9Y5K8; Q9Y688; B2RE33
• Molecular Weight: 247
• NCBI Official Full Name: V-type proton ATPase subunit D
• NCBI Official Synonym Full Names: ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
• NCBI Official Symbol: ATP6V1D
• NCBI Official Synonym Symbols: VATD; VMA8; ATP6M
• NCBI Protein Information: V-type proton ATPase subunit D; V-ATPase D subunit; V-ATPase subunit D; vacuolar H-ATPase subunit D; vacuolar proton pump D subunit; vacuolar proton pump subunit D; vacuolar ATP synthase subunit D; vacuolar proton-ATPase subunit D; V-ATPase 28 kDa accesso
• UniProt Protein Name: V-type proton ATPase subunit D
• UniProt Gene Name: ATP6V1D
• UniProt Synonym Gene Names: ATP6M; VATD; V-ATPase subunit D
• UniProt Entry Name: VATD_HUMAN

NCBI Description

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein. [provided by RefSeq, Jul 2008]

Uniprot Description

ATP6V1D: Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase D subunit family.

Protein type: EC 3.6.3.14; Hydrolase; Energy Metabolism - oxidative phosphorylation

Chromosomal Location of Human Ortholog: 14q23-q24.2

Cellular Component: centrosome; membrane; lysosomal membrane; cytosol; cilium

Molecular Function: protein binding; ATPase activity, coupled to transmembrane movement of substances

Biological Process: interaction with host; proton transport; cellular iron ion homeostasis; insulin receptor signaling pathway; cilium biogenesis; transferrin transport; transmembrane transport