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Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using MBS7128055(NPY1R Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

Rabbit anti-Human, Rat NPY1R Polyclonal Antibody | anti-NPY1R antibody

NPY1R Antibody

Gene Names
NPY1R; NPYR; NPY1-R
Reactivity
Human, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
NPY1R; Polyclonal Antibody; NPY1R Antibody; Neuropeptide Y receptor Y1; anti-NPY1R antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Applicable Applications for anti-NPY1R antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:1000-1:5000
WB: 1:500-1:2000
IHC: 1:25-1:100
Immunogen
Synthetic peptide of human NPY1R
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using MBS7128055(NPY1R Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using MBS7128055(NPY1R Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MBS7128055(NPY1R Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MBS7128055(NPY1R Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

SDS-Page

(Gel: 10%SDS-PAGE, Lysate: 60 ug, Lane: Human fetal brain tissue, Primary antibody: MBS7128055(NPY1R Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes)

SDS-Page (Gel: 10%SDS-PAGE, Lysate: 60 ug, Lane: Human fetal brain tissue, Primary antibody: MBS7128055(NPY1R Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes)
Product Categories/Family for anti-NPY1R antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,392 Da
NCBI Official Full Name
neuropeptide Y receptor type 1
NCBI Official Synonym Full Names
neuropeptide Y receptor Y1
NCBI Official Symbol
NPY1R
NCBI Official Synonym Symbols
NPYR; NPY1-R
NCBI Protein Information
neuropeptide Y receptor type 1
UniProt Protein Name
Neuropeptide Y receptor type 1
Protein Family
UniProt Gene Name
NPY1R
UniProt Synonym Gene Names
NPYR; NPYY1; NPY1-R
UniProt Entry Name
NPY1R_HUMAN

NCBI Description

Neuropeptide Y (NPY; MIM 162640) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. Two major subtypes of NPY (Y1 and Y2) have been defined by pharmacologic criteria. NPY receptors, such as NPY1R, have been identified in a variety of tissues, including brain, spleen, small intestine, kidney, testis, placenta, and aortic smooth muscle (Herzog et al., 1992 [PubMed 1321422]).[supplied by OMIM, Mar 2008]

Uniprot Description

NPY1R: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: 4q31.3-q32

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: peptide YY receptor activity; protein binding; pancreatic polypeptide receptor activity; neuropeptide Y receptor activity

Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; neuropeptide signaling pathway; regulation of blood pressure; glucose metabolic process; regulation of multicellular organism growth; locomotory behavior; feeding behavior; G-protein signaling, adenylate cyclase inhibiting pathway; sensory perception of pain

Research Articles on NPY1R

Similar Products

Product Notes

The NPY1R npy1r (Catalog #AAA7128055) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NPY1R Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NPY1R can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:1000-1:5000 WB: 1:500-1:2000 IHC: 1:25-1:100. Researchers should empirically determine the suitability of the NPY1R npy1r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NPY1R, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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