Rabbit anti-Human HIST1H1C Polyclonal Antibody | anti-HIST1H1C antibody

HIST1H1C (Ab-62) Antibody

Cat. Num. AAA7106710

• Gene Names: HIST1H1C; H1C; H1.2; H1F2; H1s-1
• Reactivity: Human
• Applications: ELISA, Immunofluorescence
• Purity: Antigen Affinity Purified
• Synonyms: HIST1H1C; Polyclonal Antibody; HIST1H1C (Ab-62) Antibody; Histone H1.2; Histone H1c; Histone H1d; Histone H1s-1; H1F2; anti-HIST1H1C antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 213

• Applicable Applications for anti-HIST1H1C antibody: ELISA (EIA), Immunofluorescence (IF)
• Application Notes: IF: 1:50-1:200
• Immunogen: Peptide sequence around site of Lys (62) derived from human Histone H1.2.
• Conjugation: Non-conjugated
• Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunofluorescence (IF)

(Immunofluorescent analysis of Hela cells using MBS7106710 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Related Product Information for anti-HIST1H1C antibody

Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).

Product Categories/Family for anti-HIST1H1C antibody

Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

• NCBI GI #: 4885375
• NCBI GeneID: 3006
• NCBI Accession #: NP_005310.1
• NCBI GenBank Nucleotide #: NM_005319.3
• UniProt Accession #: P16403; A8K4I2
• Molecular Weight: 21,365 Da
• NCBI Official Full Name: histone H1.2
• NCBI Official Synonym Full Names: histone cluster 1 H1 family member c
• NCBI Official Symbol: HIST1H1C
• NCBI Official Synonym Symbols: H1C; H1.2; H1F2; H1s-1
• NCBI Protein Information: histone H1.2
• UniProt Protein Name: Histone H1.2
• UniProt Gene Name: HIST1H1C
• UniProt Synonym Gene Names: H1F2

NCBI Description

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]

Uniprot Description

Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation ().