Rabbit anti-Lassa virus N Polyclonal Antibody | anti-N antibody
N Antibody
Reactivity
Lassa virus
Applications
ELISA
Purity
>95%, Protein G purified
Synonyms
N; Polyclonal Antibody; N Antibody; Nucleoprotein; Nucleocapsid protein; Protein N; anti-N antibody
Host
Rabbit
Reactivity
Lassa virus
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Applicable Applications for anti-N antibody
ELISA (EIA)
Immunogen
Recombinant Lassa virus Nucleoprotein (1-569AA)
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Immunogen Species
Lassa virus
Research Area
Others
Target Names
N
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Related Product Information for anti-N antibody
Description:
N polyclonal antibody MBS7052613 was produced in the rabbit immunized by using the Recombinant Lassa virus Nucleoprotein protein (1-569AA) as the immunogen. The target protein N encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). This protein serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses.
This Rabbit anti-Lassa virus N Polyclonal antibody was tested in the ELISA. The non-conjugated IgG got purified by protein G and reached up to 95% in purity. It reacts with the N proteins of lassa virus-origin and may be used to detect the endogenous levels of N protein.
N polyclonal antibody MBS7052613 was produced in the rabbit immunized by using the Recombinant Lassa virus Nucleoprotein protein (1-569AA) as the immunogen. The target protein N encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). This protein serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses.
This Rabbit anti-Lassa virus N Polyclonal antibody was tested in the ELISA. The non-conjugated IgG got purified by protein G and reached up to 95% in purity. It reacts with the N proteins of lassa virus-origin and may be used to detect the endogenous levels of N protein.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
nucleoprotein
NCBI Official Symbol
LASVsSgp1
NCBI Protein Information
nucleoprotein
UniProt Protein Name
Nucleoprotein
Protein Family
UniProt Gene Name
N
Uniprot Description
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Disables the host innate defense by interfering with beta interferon (IFNB) production through the inhibition of host IRF3 phosphorylation and activation by host IKBKE. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of IRF3, a protein involved in IFN activation pathway, leading to the inhibition of IFNB and IRF3-dependent promoters activation ().
Research Articles on N
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Product Notes
The N n (Catalog #AAA7052613) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The N Antibody reacts with Lassa virus and may cross-react with other species as described in the data sheet. AAA Biotech's N can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the N n for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "N, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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