Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Rabbit anti-Human ITSN2 Polyclonal Antibody | anti-ITSN2 antibody

ITSN2 Antibody, Biotin conjugated

Gene Names
ITSN2; SWA; SWAP; SH3D1B; SH3P18; PRO2015
Reactivity
Human
Applications
ELISA
Purity
>95%, Protein G purified
Synonyms
ITSN2; Polyclonal Antibody; ITSN2 Antibody; Biotin conjugated; Intersectin-2; SH3 domain-containing protein 1B; SH3P18; SH3P18-like WASP-associated protein; KIAA1256; SH3D1B; SWAP; anti-ITSN2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
1697
Applicable Applications for anti-ITSN2 antibody
ELISA (EIA)
Immunogen
Recombinant Human Intersectin-2 protein (940-1209AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Biotin
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-9952 / sc-9953 / sc-9954 / sc-9955
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-ITSN2 antibody
Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). Plays a role in dendrite formation by melanocytes (PubMed: 23999003).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
135,144 Da
NCBI Official Full Name
intersectin-2 isoform 1
NCBI Official Synonym Full Names
intersectin 2
NCBI Official Symbol
ITSN2
NCBI Official Synonym Symbols
SWA; SWAP; SH3D1B; SH3P18; PRO2015
NCBI Protein Information
intersectin-2
UniProt Protein Name
Intersectin-2
Protein Family
UniProt Gene Name
ITSN2
UniProt Synonym Gene Names
KIAA1256; SH3D1B; SWAP
UniProt Entry Name
ITSN2_HUMAN

NCBI Description

This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. [provided by RefSeq, Jan 2017]

Uniprot Description

ITSN2: adapter protein that contains SH3 domains. Involved in the formation of clathrin-coated vesicles. May function in the induction of T cell antigen receptor (TCR) endocytosis. May provide indirect link between the endocytic membrane traffic and the actin assembly machinery. Three alternatively spliced isoforms have been described.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: centrosome

Molecular Function: protein binding; SH3/SH2 adaptor activity

Research Articles on ITSN2

Similar Products

Product Notes

The ITSN2 itsn2 (Catalog #AAA7051255) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ITSN2 Antibody, Biotin conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ITSN2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the ITSN2 itsn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ITSN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.