Rabbit anti-Human TIMM17B Polyclonal Antibody | anti-TIMM17B antibody

TIMM17B Antibody

Cat. Num. AAA7046614

• Gene Names: TIMM17B; JM3; TIM17B; DXS9822
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Antigen Affinity Purified
• Synonyms: TIMM17B; Polyclonal Antibody; TIMM17B Antibody; Mitochondrial import inner membrane translocase subunit Tim17-B; TIM17B; JM3; anti-TIMM17B antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 222

• Applicable Applications for anti-TIMM17B antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Species: Human
• Immunogen: Recombinant human Mitochondrial import inner membrane translocase subunit Tim17-B protein (1-172AA)
• Conjugate: Non-conjugated
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: TIMM17B antibody at 1.75 ug/mlLane 1: U251 whole cell lysateLane 2: Jurkat whole cell lysateLane 3: HepG-2 whole cell lysateLane 4: HL60 whole cell lysateLane 5: A431 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 19,24 kDaObserved band size: 18 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human colon cancer using MBS7046614 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7046614 at dilution of 1:100)

Related Product Information for anti-TIMM17B antibody

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.

NCBI and Uniprot Product Information

• NCBI GI #: 269784613
• NCBI GeneID: 10245
• NCBI Accession #: NP_001161419.1
• NCBI GenBank Nucleotide #: NM_001167947.2
• UniProt Accession #: O60830; Q9UJV0; A8K2E2; J3KPV3
• Molecular Weight: 23,824 Da
• NCBI Official Full Name: mitochondrial import inner membrane translocase subunit Tim17-B isoform 1
• NCBI Official Synonym Full Names: translocase of inner mitochondrial membrane 17 homolog B (yeast)
• NCBI Official Symbol: TIMM17B
• NCBI Official Synonym Symbols: JM3; TIM17B; DXS9822
• NCBI Protein Information: mitochondrial import inner membrane translocase subunit Tim17-B
• UniProt Protein Name: Mitochondrial import inner membrane translocase subunit Tim17-B
• Protein Family: Mitochondrial import inner membrane translocase
• UniProt Gene Name: TIMM17B
• UniProt Synonym Gene Names: TIM17B
• UniProt Entry Name: TI17B_HUMAN

NCBI Description

This gene encodes a multipass transmembrane protein that forms an integral component of the mitochondrial translocase TIM23 complex. This complex facilitates the transport of mitochondrial proteins from the cytosol across the mitochondrial inner membrane and into the mitochondrion. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Uniprot Description

TIMM17B: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Belongs to the Tim17/Tim22/Tim23 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Transporter

Chromosomal Location of Human Ortholog: Xp11.23

Cellular Component: integral to mitochondrial inner membrane; mitochondrial inner membrane; mitochondrial inner membrane presequence translocase complex

Molecular Function: protein channel activity

Biological Process: protein import into mitochondrial matrix; protein targeting to mitochondrion