Mu-type opioid receptor (Oprm1) Recombinant Protein | Oprm1 recombinant protein
Recombinant Mouse Mu-type opioid receptor (Oprm1)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the mu opioid receptor which is where drugs such as morphine and other opioids have pharmacological effects. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
Uniprot Description
MOR-1: a Gi-protein-coupled receptor for beta-endorphin, morphine and other opiates. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Ligand-binding inactivates adenylyl cyclase, and activates a variety of G-beta-gamma-dependent pathways including the MAPK and the PI3K/Akt cascades. Two splice-variant isoforms have been described.
Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass
Cellular Component: cell; cytoplasm; dendrite; dendrite cytoplasm; focal adhesion; integral to membrane; integral to plasma membrane; lipid raft; membrane; neuron projection; perikaryon; plasma membrane; sarcolemma
Molecular Function: beta-endorphin receptor activity; filamin binding; G-protein alpha-subunit binding; G-protein beta-subunit binding; G-protein coupled receptor activity; neuropeptide binding; opioid receptor activity; protein binding; protein C-terminus binding; protein domain specific binding; signal transducer activity; voltage-gated calcium channel activity
Biological Process: behavioral response to ethanol; cellular response to stress; dopamine receptor, adenylate cyclase activating pathway; eating behavior; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); locomotory behavior; negative regulation of adenylate cyclase activity; negative regulation of cAMP biosynthetic process; negative regulation of nitric oxide biosynthetic process; neuropeptide signaling pathway; opioid receptor, adenylate cyclase inhibiting pathway; positive regulation of appetite; positive regulation of neurogenesis; positive regulation of nitric oxide biosynthetic process; reduction of cytosolic calcium ion concentration; regulation of excitatory postsynaptic membrane potential; regulation of sensory perception of pain; response to ethanol; sensory perception of pain; signal transduction; synaptic transmission
Research Articles on Oprm1
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Product Notes
The Oprm1 oprm1 (Catalog #AAA7024638) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-398aa; Full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the Oprm1 oprm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MDSSAGPGNI SDCSDPLAPA SCSPAPGSWL NLSHVDGNQS DPCGPNRTGL GGSHSLCPQT GSPSMVTAIT IMALYSIVCV VGLFGNFLVM YVIVRYTKMK TATNIYIFNL ALADALATST LPFQSVNYLM GTWPFGNILC KIVISIDYYN MFTSIFTLCT MSVDRYIAVC HPVKALDFRT PRNAKIVNVC NWILSSAIGL PVMFMATTKY RQGSIDCTLT FSHPTWYWEN LLKICVFIFA FIMPVLIITV CYGLMILRLK SVRMLSGSKE KDRNLRRITR MVLVVVAVFI VCWTPIHIYV IIKALITIPE TTFQTVSWHF CIALGYTNSC LNPVLYAFLD ENFKRCFREF CIPTSSTIEQ QNSARIRQNT REHPSTANTV DRTNHQLENL EAETAPLP. It is sometimes possible for the material contained within the vial of "Mu-type opioid receptor (Oprm1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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