Rabbit anti-Human, mouse ABI3 Polyclonal Antibody | anti-ABI3 antibody
ABI3 Antibody
Western Blot (WB)
(Western blotAll lanes: ABI3 antibody at 5ug/ml+Mouse heart tissueGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 40,39 kDaObserved band size: 39 kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human tonsil tissue using MBS7006080 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human placenta tissue using MBS7006080 at dilution of 1:100)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Uniprot Description
ABI3: May inhibit tumor metastasis. In vitro, reduces cell motility. Belongs to the ABI family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 17q21.3
Cellular Component: cytoplasm; intracellular; lamellipodium; membrane
Molecular Function: protein binding
Biological Process: cell motility; peptidyl-tyrosine phosphorylation; regulation of cell migration
Research Articles on ABI3
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Product Notes
The ABI3 abi3 (Catalog #AAA7006080) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ABI3 Antibody reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ABI3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Recommended dilution: WB:1:500-2000, IHC:1:20-1:200. Researchers should empirically determine the suitability of the ABI3 abi3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ABI3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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