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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7002272 at dilution of 1:100)

Rabbit anti-Human DPH6 Polyclonal Antibody | anti-DPH6 antibody

DPH6 Antibody

Gene Names
DPH6; ATPBD4
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
>95%,Protein G purified
Synonyms
DPH6; Polyclonal Antibody; DPH6 Antibody; Diphthine--ammonia ligase; ATP-binding domain-containing protein 4; Diphthamide synthase; Diphthamide synthetase; Protein DPH6 homolog; ATPBD4; anti-DPH6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Sequence Length
165
Applicable Applications for anti-DPH6 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Immunogen
Recombinant human Diphthine--ammonia ligase protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-169978
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7002272 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7002272 at dilution of 1:100)

Immunofluorescence (IF)

(Immunofluorescent analysis of HepG2 cells using MBS7002272 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunofluorescence (IF) (Immunofluorescent analysis of HepG2 cells using MBS7002272 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-DPH6 antibody
Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP. Diphthamide biosynthesis consists in the conversion of an L-histidine residue in the translation elongation factor (EEF2) to diphthamide.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18,657 Da
NCBI Official Full Name
diphthine--ammonia ligase isoform 2
NCBI Official Synonym Full Names
diphthamine biosynthesis 6
NCBI Official Symbol
DPH6
NCBI Official Synonym Symbols
ATPBD4
NCBI Protein Information
diphthine--ammonia ligase
UniProt Protein Name
Diphthine--ammonia ligase
Protein Family
UniProt Gene Name
DPH6
UniProt Synonym Gene Names
ATPBD4
UniProt Entry Name
DPH6_HUMAN

Uniprot Description

DPH6: Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP. Diphthamide biosynthesis consists in the conversion of an L-histidine residue in the translation elongation factor (EEF2) to diphthamide. Belongs to the Diphthine--ammonia ligase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 6.3.1.14

Chromosomal Location of Human Ortholog: 15q14

Cellular Component: cytosol; nucleolus; nucleus

Molecular Function: ATP binding; diphthine-ammonia ligase activity

Biological Process: cellular protein metabolic process; peptidyl-diphthamide biosynthetic process from peptidyl-histidine; post-translational protein modification; regulation of protein stability

Research Articles on DPH6

Similar Products

Product Notes

The DPH6 dph6 (Catalog #AAA7002272) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DPH6 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DPH6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the DPH6 dph6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DPH6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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