Rabbit anti-Human FGD6 Polyclonal Antibody | anti-FGD6 antibody

FGD6 Antibody

Cat. Num. AAA7001428

• Gene Names: FGD6; ZFYVE24
• Reactivity: Human
• Applications: ELISA
• Purity: >95%,Protein G purified
• Synonyms: FGD6; Polyclonal Antibody; FGD6 Antibody; FYVE; RhoGEF and PH domain-containing protein 6; Zinc finger FYVE domain-containing protein 24; KIAA1362; ZFYVE24; anti-FGD6 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%,Protein G purified
• Form/Format: Liquid
• Sequence Length: 1430

• Applicable Applications for anti-FGD6 antibody: ELISA (EIA)
• Immunogen: Recombinant human FYVE, RhoGEF and PH domain-containing protein 6 protein
• Conjugation: Non-conjugated
• Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Preparation and Storage: Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Western Blot (WB)

(Western BlotPositive WB detected in: K562 whole cell lysateAll lanes: FGD6 antibody at 2.8ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 161,156 KDaObserved band size: 161 KDa)

Immunocytochemistry (ICC)

(Immunocytochemistry analysis of human brain tissue using MBS7001428 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunocytochemistry analysis of human adrenal gland tissue using MBS7001428 at dilution of 1:100)

Related Product Information for anti-FGD6 antibody

May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape.

NCBI and Uniprot Product Information

• NCBI GI #: 154240686
• NCBI GeneID: 55785
• NCBI Accession #: NP_060821.3
• NCBI GenBank Nucleotide #: NM_018351.3
• UniProt Accession #: Q6ZV73; Q6ZR53; Q7Z2Z7; Q96D44; Q9NUR8; Q9P2I5
• Molecular Weight: 154,465 Da
• NCBI Official Full Name: FYVE, RhoGEF and PH domain-containing protein 6
• NCBI Official Synonym Full Names: FYVE, RhoGEF and PH domain containing 6
• NCBI Official Symbol: FGD6
• NCBI Official Synonym Symbols: ZFYVE24
• NCBI Protein Information: FYVE, RhoGEF and PH domain-containing protein 6
• UniProt Protein Name: FYVE, RhoGEF and PH domain-containing protein 6
• Protein Family: FYVE, RhoGEF and PH domain-containing protein
• UniProt Gene Name: FGD6
• UniProt Synonym Gene Names: KIAA1362; ZFYVE24
• UniProt Entry Name: FGD6_HUMAN

Uniprot Description

FGD6: May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GEFs; GEFs, Rac/Rho

Chromosomal Location of Human Ortholog: 12q22

Cellular Component: cytoplasm; cytoskeleton; Golgi apparatus; lamellipodium; ruffle

Molecular Function: guanyl-nucleotide exchange factor activity; metal ion binding; Rho guanyl-nucleotide exchange factor activity; small GTPase binding

Biological Process: actin cytoskeleton organization and biogenesis; cytoskeleton organization and biogenesis; filopodium formation; positive regulation of GTPase activity; regulation of cell shape; regulation of GTPase activity; regulation of Rho protein signal transduction