GDF-15/MIC-1 active protein
Human GDF-15/MIC-1
NCBI and Uniprot Product Information
NCBI Description
Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.[supplied by OMIM, Oct 2009]
Uniprot Description
Function: Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter
By similarity. RuleBase RU000684
Catalytic activity: ATP + H2O = ADP + phosphate. RuleBase RU000684
Sequence similarities: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily. [View classification] RuleBase RU000684Contains 2 ABC transmembrane type-1 domains. RuleBase RU000684Contains 2 ABC transporter domains. RuleBase RU000684
Research Articles on GDF-15/MIC-1
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Product Notes
The GDF-15/MIC-1 cftr (Catalog #AAA691500) is an Active Protein produced from Cell Culture and is intended for research purposes only. The product is available for immediate purchase. The Human GDF-15/MIC-1 reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: ARNGDHCPLG PGRCCRLHTV RASLEDLGWA DWVLSPREVQ VTMCIG ACPS QFRAANMHAQ IKTSLHRLKP DTVPAPCCVP ASYNPMVLIQ K TDTGVSLQT YDDLLAKDCH CI. It is sometimes possible for the material contained within the vial of "GDF-15/MIC-1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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