Western Blot (WB)
(Expression analysis of NALP10. Anti-NALP10 antibody (11-3011) was used at 2 ug/ml on HepG2 lysate.)
Rabbit anti-Human NALP10 Polyclonal Antibody | anti-NLRP10 antibody
NALP10
Western Blot (WB)
(Expression analysis of NALP10. Anti-NALP10 antibody (11-3011) was used at 2 ug/ml on HepG2 lysate.)
Western Blot (WB)
(Expression analysis of NALP10. Anti-NALP10 antibody (11-3011) was used at 2 ug/ml on HepG2 lysate.)
NCBI and Uniprot Product Information
NCBI Description
Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq, Jul 2008]
Uniprot Description
NALP10: Inhibits CASP1/caspase-1-dependent IL1B secretion and PYCARD-mediated apoptosis, but not that induced by FAS or BID. Belongs to the NLRP family.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 11p15.4
Cellular Component: cytoplasm; extrinsic to plasma membrane
Biological Process: defense response to fungus; defense response to Gram-negative bacterium; positive regulation of T-helper 1 type immune response
Research Articles on NLRP10
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Product Notes
The NLRP10 nlrp10 (Catalog #AAA668246) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NALP10 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NALP10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the NLRP10 nlrp10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NALP10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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