Mouse anti-Human Hid-5/S100A7/Psoriasin Monoclonal Antibody | anti-S100A7 antibody

Hid-5/S100A7/Psoriasin

Cat. Num. AAA668214

• Gene Names: S100A7; PSOR1; S100A7c
• Reactivity: Human
• Applications: Western Blot
• Purity: Protein G purification
• Synonyms: Hid-5/S100A7/Psoriasin; Monoclonal Antibody; anti-S100A7 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1, Kappa
• Clone Number: ABM18A5
• Purity/Purification: Protein G purification
• Form/Format: Purified
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 101

• Applicable Applications for anti-S100A7 antibody: Western Blot (WB)
• Immunogen: A partial length recombinant human psoriasin/HID-5 protein was used as the immunogen for this antibody.
• Buffer: PBS containing 0.05% BSA and 0.05% sodium azide.
• Target Modification: No
• Produced from Ascites: No
• Preparation and Storage: Store the antibody at 4 degree C, stable for 6 months. For long-term storage, store at -20 degree C. Avoid repeated freeze and thaw cycles.

Western Blot (WB)

(Expression analysis of Hid-5. Anti-Hid-5 antibody (Clone: ABM18A5) was tested at 2 ug/ml on BT-474 lysate.)

NCBI and Uniprot Product Information

• NCBI GI #: 115298657
• NCBI GeneID: 6278
• NCBI Accession #: NP_002954.2
• NCBI GenBank Nucleotide #: NM_002963.3
• UniProt Accession #: P31151; Q5SY67; Q6FGE3; Q9H1E2
• Molecular Weight: 11,471 Da
• NCBI Official Full Name: protein S100-A7
• NCBI Official Synonym Full Names: S100 calcium binding protein A7
• NCBI Official Symbol: S100A7
• NCBI Official Synonym Symbols: PSOR1; S100A7c
• NCBI Protein Information: protein S100-A7
• UniProt Protein Name: Protein S100-A7
• Protein Family: Protein
• UniProt Gene Name: S100A7
• UniProt Synonym Gene Names: PSOR1; S100A7C
• UniProt Entry Name: S10A7_HUMAN

NCBI Description

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014]

Uniprot Description

S100A7: is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known. [provided by RefSeq, Jul 2008]

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: cytoplasm; cytosol; endoplasmic reticulum; extracellular region; focal adhesion; nucleus

Molecular Function: calcium ion binding; protein binding; RAGE receptor binding; zinc ion binding

Biological Process: angiogenesis; defense response to Gram-negative bacterium; epidermis development; innate immune response; keratinocyte differentiation; response to lipopolysaccharide; response to reactive oxygen species; sequestering of metal ion