Lactoperoxidase Enzyme | LPO enzyme
Lactoperoxidase (LPO, EC 1.11.1.7)
Iodide reacts directly with the heme group; upon addition of H2O2 the complex iodinates the substrate. LPO is inhibited by hydrazines. The assay procedure has been updated from that of Morrison to an ABTS®/H2O2 based method with increased sensitivity and reproducibility.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an oxidoreductase secreted from salivary, mammary, and other mucosal glands that functions as a natural antibacterial agent. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Uniprot Description
Function: May contribute to airway host defense against infection. Ref.7
Catalytic activity: 2 phenolic donor + H2O2 = 2 phenoxyl radical of the donor + 2 H2O.
Cofactor: Binds 1 calcium ion per heterodimer
By similarity.Binds 1 heme B (iron-protoporphyrin IX) group covalently per heterodimer
By similarity.
Subcellular location: Secreted › extracellular space.
Tissue specificity: Mammary gland; milk and salivary gland. Found in bronchial submucosal glands. Ref.7
Sequence similarities: Belongs to the peroxidase family. XPO subfamily.
Research Articles on LPO
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Product Notes
The LPO lpo (Catalog #AAA653640) is an Enzyme produced from Bovine milk and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Lactoperoxidase, Enzyme" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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