Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Rat Monoamine oxidase B (MAOB) Standard Curve.)
Rat Monoamine Oxidase B (MAOB) ELISA Kit | MAOB elisa kit
Rat Monoamine Oxidase B (MAOB) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Rat Monoamine oxidase B (MAOB) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Rat Monoamine oxidase B (MAOB) Standard Curve.)
Background: Monoamine oxidase B, is a protein belongs to the flavin monoamine oxidase family. It is an enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine.Edmondson et al. described structural features of the human enzyme: it has a hydrophobic bipartite elongated cavity that (for the "open" conformation) occupies a combined volume close to 700 Å2. hMAO-A has a single cavity that exhibits a rounder shape and is larger in volume than the "substrate cavity" of hMAO-B.
NCBI and Uniprot Product Information
NCBI Description
major neurotransmitter-degrading enzyme in the CNS; degrades biogenic monoamines in the brain [RGD, Feb 2006]
Uniprot Description
MAOB: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. Belongs to the flavin monoamine oxidase family.
Protein type: Membrane protein, integral; Mitochondrial; Oxidoreductase; EC 1.4.3.4; Amino Acid Metabolism - histidine; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - glycine, serine and threonine; Amino Acid Metabolism - tryptophan; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - arginine and proline
Cellular Component: mitochondrial outer membrane; mitochondrion; mitochondrial inner membrane; integral to membrane
Molecular Function: amine oxidase activity; protein homodimerization activity; FAD binding; oxidoreductase activity
Biological Process: response to drug; positive regulation of dopamine metabolic process; negative regulation of serotonin secretion; response to selenium ion; response to ethanol; neurotransmitter catabolic process; substantia nigra development; response to steroid hormone stimulus; response to toxin; response to lipopolysaccharide; response to aluminum ion; response to corticosterone stimulus
Research Articles on MAOB
Similar Products
Product Notes
The Rat MAOB maob (Catalog #AAA9712338) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9712338 ELISA Kit recognizes Rat MAOB. It is sometimes possible for the material contained within the vial of "Monoamine Oxidase B (MAOB), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
