Rabbit anti-Human, Mouse POLD3 Polyclonal Antibody | anti-POLD3 antibody
POLD3, CT (POLD3, KIAA0039, DNA polymerase delta subunit 3, DNA polymerase delta subunit p66)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Western Blot (WB)
(POLD3 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the POLD3 antibody detected the POLD3 protein (arrow).)
Western Blot (WB)
(POLD3 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the POLD3 antibody detected the POLD3 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012]
Uniprot Description
Function: Required for optimal DNA polymerase delta activity. Ref.5 Ref.6 Ref.8
Subunit structure: Heterotetramer composed of subunits of 125 kDa, 50 kDa, 66 kDa and 12 kDa. Interacts with POLD2. Interacts with PCNA. Ref.8
Subcellular location: Nucleus.
Sequence caution: The sequence BAA05039.1 differs from that shown. Reason: Erroneous initiation.
Research Articles on POLD3
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Product Notes
The POLD3 pold3 (Catalog #AAA649947) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The POLD3, CT (POLD3, KIAA0039, DNA polymerase delta subunit 3, DNA polymerase delta subunit p66) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's POLD3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the POLD3 pold3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "POLD3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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