Rat anti-Mouse Marapsin Monoclonal Antibody | anti-PRSS27 antibody
Marapsin
Reactivity
Mouse
Applications
ELISA
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
Marapsin; Monoclonal Antibody; Anti -Marapsin; anti-PRSS27 antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
11D23
Specificity
Recognizes mouse Marapsin.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with sterile PBS.
Applicable Applications for anti-PRSS27 antibody
ELISA (EL/EIA)
Application Notes
Suitable for use in ELISA.
Dilution: ELISA: 2-8ug/ml
Dilution: ELISA: 2-8ug/ml
Immunogen
Recombinant corresponding to mouse Marapsin expressed in NSO cells (Q8BJR6).
Hybridoma
Myeloma cells with B cells from Balb/c mice.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-PRSS27 antibody
Marapsin is a 40 to 41kD serine peptidase that is transcribed strongly in the pancreas. The 6-exon organization of the gene is shared by a small group of tryptic proteases, including prostasin, testisin, and y-tryptase. The Marapsin gene, like these other genes, resides on chromosome 16p. Mouse Marapsin cDNA predicts a 328aa precursor that contains a 22aa signal sequence, a 15aa propeptide, and a 29aa mature chain. There is one potential site for N-linked glycosylation. Mouse Marapsin contains a carboxyl-terminal membrane anchor, which human Marapsin lacks. Mouse Marapsin is 89% and 70% aa identical to rat and human Marapsin, respectively. Marapsin has preferences for hydrolysis of extended peptide substrates which feature a strong preference for P1 Arg and differ from those of trypsin. Marapsin is inhibited by benzamidine and leupeptin but resists several classic inhibitors of trypsin. Thus, Marapsin is a secreted, tryptic serine protease of the pancreas with novel physical and enzymatic properties.
Product Categories/Family for anti-PRSS27 antibody
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
31,940 Da
NCBI Official Full Name
marapsin
UniProt Protein Name
Serine protease 27
Protein Family
UniProt Gene Name
PRSS27
UniProt Synonym Gene Names
MPN
UniProt Entry Name
PRS27_HUMAN
Uniprot Description
Subcellular location: Secreted.
Tissue specificity: Expressed predominantly in the pancreas. Ref.3
Post-translational modification: N-glycosylated. Ref.3
Sequence similarities: Belongs to the peptidase S1 family.Contains 1 peptidase S1 domain.
Similar Products
Product Notes
The Marapsin prss27 (Catalog #AAA649413) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Marapsin reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Marapsin can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA. Dilution: ELISA: 2-8ug/ml. Researchers should empirically determine the suitability of the Marapsin prss27 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Marapsin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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