Rabbit NOT1 Polyclonal Antibody | anti-NOT1 antibody
NOT1 (NURR1, Cys4 Zinc Finger Nuclear Receptor Type Family Transcription Factor) (AP)
Gene Names
NR4A2; NOT; RNR1; HZF-3; NURR1; TINUR
Reactivity
Human, Rodent
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Purified by affinity chromatography.
Synonyms
NOT1; Polyclonal Antibody; NOT1 (NURR1; Cys4 Zinc Finger Nuclear Receptor Type Family Transcription Factor) (AP); anti-NOT1 antibody
Host
Rabbit
Reactivity
Human, Rodent
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes Nurr1/NOT1 (Cys4 zinc finger of nuclear receptor type family), a zinc finger transcription factor. Species crossreactivity: rodent.
Purity/Purification
Purified by affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase.
Applicable Applications for anti-NOT1 antibody
Immunohistochemistry (IHC) Frozen, Western Blot (WB), ELISA (EIA)
Application Notes
IHC: Frozen sections. Not tested for paraffin. 1:100-1:1000
WB: 1:100-1:1000 (ECL)
Applications are based on unconjugated antibody.
WB: 1:100-1:1000 (ECL)
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide to NOT1
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Product Categories/Family for anti-NOT1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
59,809 Da
NCBI Official Full Name
Homo sapiens nuclear receptor subfamily 4, group A, member 2 (NR4A2), mRNA
NCBI Official Synonym Full Names
nuclear receptor subfamily 4, group A, member 2
NCBI Official Symbol
NR4A2
NCBI Official Synonym Symbols
NOT; RNR1; HZF-3; NURR1; TINUR
NCBI Protein Information
nuclear receptor subfamily 4 group A member 2; NGFI-B/nur77 beta-type transcription factor homolog; T-cell nuclear receptor NOT; immediate-early response protein NOT; intermediate-early receptor protein; nuclear receptor related 1; nur related protein-1,
UniProt Protein Name
Nuclear receptor subfamily 4 group A member 2
Protein Family
UniProt Gene Name
NR4A2
UniProt Synonym Gene Names
NOT; NURR1; TINUR
UniProt Entry Name
NR4A2_HUMAN
NCBI Description
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons ().
Research Articles on NOT1
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Product Notes
The NOT1 nr4a2 (Catalog #AAA6490319) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NOT1 (NURR1, Cys4 Zinc Finger Nuclear Receptor Type Family Transcription Factor) (AP) reacts with Human, Rodent and may cross-react with other species as described in the data sheet. AAA Biotech's NOT1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Frozen, Western Blot (WB), ELISA (EIA). IHC: Frozen sections. Not tested for paraffin. 1:100-1:1000 WB: 1:100-1:1000 (ECL) Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the NOT1 nr4a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NOT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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