Goat anti-Human Nucleoporin 107kDa Polyclonal Antibody | anti-NUP107 antibody

Nucleoporin 107kDa (NUP 107, NUP107, NUP-107, 107kD Nucleoporin, Nuclear Pore Complex Protein Nup107, Nucleoporin Nup107, NUP84)

Cat. Num. AAA648801

• Gene Names: NUP107; NUP84
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: Nucleoporin 107kDa; Polyclonal Antibody; Nucleoporin 107kDa (NUP 107; NUP107; NUP-107; 107kD Nucleoporin; Nuclear Pore Complex Protein Nup107; Nucleoporin Nup107; NUP84); Anti -Nucleoporin 107kDa (NUP 107; anti-NUP107 antibody

• Host: Goat
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: Recognizes human NUP107. Species sequence homology: Mouse, rat, canine and bovine.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

• Applicable Applications for anti-NUP107 antibody: Western Blot (WB)
• Application Notes: Suitable for use in ELISA and Western Blot.; Dilution: ELISA: 1:8000; Western Blot: 1-3ug/ml
• Immunogen: Synthetic peptide corresponding to C-PLPAEDDNAIREH of human NUP107.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Chemiluminescence

(MBS648801 (1ug/ml) staining of Peripheral Blood Lymphocytes lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Product Categories/Family for anti-NUP107 antibody

Antibodies; Abs to Nuclear Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 9966881
• NCBI GeneID: 57122
• NCBI Accession #: NP_065134.1
• NCBI GenBank Nucleotide #: NM_020401.2
• UniProt Accession #: P57740
• Molecular Weight: 106,374 Da
• NCBI Official Full Name: nuclear pore complex protein Nup107
• NCBI Official Synonym Full Names: nucleoporin 107kDa
• NCBI Official Symbol: NUP107
• NCBI Official Synonym Symbols: NUP84
• NCBI Protein Information: nuclear pore complex protein Nup107; nucleoporin Nup107; 107 kDa nucleoporin
• UniProt Protein Name: Nuclear pore complex protein Nup107
• Protein Family: Nucleoporin
• UniProt Gene Name: NUP107
• UniProt Entry Name: NU107_HUMAN

NCBI Description

This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

Uniprot Description

Function: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Ref.6 Ref.7

Subunit structure: Part of the nuclear pore complex (NPC). Forms part of the Nup160 subcomplex in the nuclear pore which is composed of NUP160, NUP133, NUP107 and Nup96; this complex plays a role in RNA export and in tethering Nup98 and NUP153 to the nucleus. Does not interact with TPR. Ref.3 Ref.4 Ref.7

Subcellular location: Nucleus membrane. Nucleus › nuclear pore complex. Chromosome › centromere › kinetochore. Note: Located on both the cytoplasmic and nuclear sides of the NPC core structure. During mitosis, localizes to the kinetochores. Dissociates from the dissasembled NPC structure late during prophase of mitosis. Ref.3 Ref.4 Ref.5 Ref.7

Sequence similarities: Belongs to the nucleoporin Nup84/Nup107 family.