Rabbit anti-Mouse NUP107 Polyclonal Antibody | anti-NUP107 antibody

NUP107, ID (NUP107, Nuclear pore complex protein Nup107, 107kD nucleoporin, Nucleoporin Nup107) (Azide free) (HRP)

Cat. Num. AAA6327231

• Gene Names: NUP107; NUP84
• Reactivity: Mouse
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: NUP107; Polyclonal Antibody; ID (NUP107; Nuclear pore complex protein Nup107; 107kD nucleoporin; Nucleoporin Nup107) (Azide free) (HRP); Nucleoporin Nup107; anti-NUP107 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

• Applicable Applications for anti-NUP107 antibody: Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
• Application Notes: IHC: 1:50-100; ELISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: NUP107 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-433 amino acids from the Central region of human NUP107.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(NUP107 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the NUP107 antibody detected the NUP107 protein (arrow).)

Immunohistochemistry (IHC)

(NUP107 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervical tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NUP107 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-NUP107 antibody

This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Product Categories/Family for anti-NUP107 antibody

Antibodies; Nuclear Proteins

References

Kim, S.Y., et al. Biochem. Biophys. Res. Commun. 401(1):131-136(2010). Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010). Mishra, R.K., et al. Nat. Cell Biol. 12(2):164-169(2010). Platani, M., et al. Mol. Biol. Cell 20(24):5260-5275(2009). Whittle, J.R., et al. J. Biol. Chem. 284(41):28442-28452(2009).

NCBI and Uniprot Product Information

• NCBI GI #: 9966881
• NCBI GeneID: 57122
• NCBI Accession #: NP_065134.1
• NCBI GenBank Nucleotide #: NM_020401.2
• UniProt Accession #: P57740
• Molecular Weight: 106,374 Da
• NCBI Official Full Name: nuclear pore complex protein Nup107
• NCBI Official Synonym Full Names: nucleoporin 107kDa
• NCBI Official Symbol: NUP107
• NCBI Official Synonym Symbols: NUP84
• NCBI Protein Information: nuclear pore complex protein Nup107; nucleoporin Nup107; 107 kDa nucleoporin
• UniProt Protein Name: Nuclear pore complex protein Nup107
• Protein Family: Nucleoporin
• UniProt Gene Name: NUP107
• UniProt Entry Name: NU107_HUMAN

NCBI Description

This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

Uniprot Description

NUP107: Essential component of nuclear pore complex. Required for the assembly of peripheral proteins into the nuclear pore complex. Belongs to the nucleoporin Nup84/Nup107 family.

Protein type: Nucleoporin

Chromosomal Location of Human Ortholog: 12q15

Cellular Component: nucleoplasm; kinetochore; centrosome; nuclear membrane; membrane; nuclear pore; nuclear envelope; cytosol

Molecular Function: protein binding; structural constituent of nuclear pore; nucleocytoplasmic transporter activity

Biological Process: nuclear pore complex assembly; viral reproduction; cytokine and chemokine mediated signaling pathway; mitotic nuclear envelope disassembly; pathogenesis; glucose transport; viral infectious cycle; mRNA export from nucleus; protein transport; hexose transport; carbohydrate metabolic process; gene expression; viral transcription; mitotic cell cycle; transmembrane transport