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Bax Recombinant Protein

Bax, Recombinant, Mouse (BCL2-associated X protein, Apoptosis regulator BAX)

Purity
Highly Purified
95% as determined by RP-HPLC, and/or reducing and non-reducing SDS-PAGE Silver Stained gel.
Synonyms
Bax; Recombinant; Mouse (BCL2-associated X protein; Apoptosis regulator BAX); Bax recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Highly Purified
95% as determined by RP-HPLC, and/or reducing and non-reducing SDS-PAGE Silver Stained gel.
Form/Format
Supplied as a liquid in 10mM Tris-HCl, pH 8.0, 1mM EDTA and 250mM sodium chloride.
Application Notes
Suitable for use as Input marker or positive control (Western Blot) and Function study (binding assay).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for Bax recombinant protein
Bcl-2-associated X protein (Bax) belongs to the Bcl-2 protein family. Bax is a pro-apoptotic Bcl-2 protein containing BH1, BH2 and BH3 domains. Bax accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor bcl2 or its adenovirus homolog e1b 19k protein. Bax induces the release of cytochrome c, activation of casp3, and thereby apoptosis. Bax is expressed in a wide variety of tissues, with highest levels in the testis and ovary. Tumor suppressor protein p53 upregulates the expression of BAX. Bax has been shown to be involved in p53-mediated apoptosis.

Recombinant Mouse Bax, amino acids 38-171, produced in E.Coli, is a single, non-glycosylated polypeptide chain. Recombinant Mouse Bax is purified by proprietary chromatographic techniques.
Product Categories/Family for Bax recombinant protein

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Product Notes

The Bax (Catalog #AAA638142) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. Suitable for use as Input marker or positive control (Western Blot) and Function study (binding assay). Researchers should empirically determine the suitability of the Bax for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bax, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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