Nampt, Rat Recombinant Protein | Nampt recombinant protein
Nampt, Recombinant, Rat (Visfatin/PBEF, PBEF1, Pre-B Cell Colony Enhancing Factor 1, Nicotinamide Phosphoribosyltransferase)
>90% (SDS-PAGE)
>90% (SDS-PAGE)
Long-term Storage: -20 degree C
Working aliquots are stable for up to 3 months when stored at -20 degree C.
NCBI and Uniprot Product Information
NCBI Description
has similarity to cytokines but is not secreted; localized to the nucleus and cytoplasm, changes in subcellular localization may be associated with the cell cycle [RGD, Feb 2006]
Uniprot Description
PBEF: an ubiquitous protein originally described as a cytokine which acts on early B-lineage precursor cells. Other reports indicate that PBEF is not a cytokine-like secreted protein but an intracellular protein associated with the cell cycle. Contains a catalytically active nicotinate phosphoribosyltransferase domain, an enzyme involved in nicotinamide adenine dinucleotide (NAD) biosynthesis.
Protein type: Cytokine; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; EC 2.4.2.12; Transferase; Cell cycle regulation
Cellular Component: extracellular space; cytoplasm; nucleus
Molecular Function: protein homodimerization activity; cytokine activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity; drug binding; nicotinamide phosphoribosyltransferase activity
Biological Process: NAD biosynthetic process; positive regulation of smooth muscle cell proliferation; insulin receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; female pregnancy; circadian regulation of gene expression; response to organic cyclic substance; positive regulation of nitric-oxide synthase biosynthetic process
Research Articles on Nampt
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Product Notes
The Nampt nampt (Catalog #AAA637713) is a Recombinant Protein produced from Rat, HEK 293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Rat Nampt (visfatin/ PBEF) (aa 1-491) is fused at the N-terminus to a DYKDDDDK-t ag. It is sometimes possible for the material contained within the vial of "Nampt, Rat, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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