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SDS-Page (SDS-PAGE on the purified Saporin protein.)

Saporin Active Protein | SAP2 active protein

Saporin (Saponaria officinalis, Common Soapwort, ribosome inactivating protein saporin-6, SAP-6, SO-6, rRNA N-glycosidase)

Applications
ELISA
Purity
Highly Purified
~95% by SDS-PAGE and Western Blot.
Synonyms
Saporin; Saporin (Saponaria officinalis; Common Soapwort; ribosome inactivating protein saporin-6; SAP-6; SO-6; rRNA N-glycosidase); SAP2 active protein
Ordering
For Research Use Only!
Purity/Purification
Highly Purified
~95% by SDS-PAGE and Western Blot.
Form/Format
Supplied as a lyophilized powder. Reconstitute with sterile buffer.
Applicable Applications for SAP2 active protein
ELISA (EL/EIA)
Application Notes
Suitable for use in ELISA.
Biological Activity
Upon introduction into the cells, saporin will arrest the protein synthesis by damaging the ribosmes.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile buffer. Aliquot and store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

SDS-Page

(SDS-PAGE on the purified Saporin protein.)

SDS-Page (SDS-PAGE on the purified Saporin protein.)
Related Product Information for SAP2 active protein
Saporin is a ribosome-inactivating protein (RIP) of type I. This monomeric RNA N-glycosidase purified from seeds of the plant Saponaria officinalis also known as Soapwort, is capable of specific depurination of eukaryotic ribosomes thus arresting protein synthesis. No ligand has been identified in saporin hence its inability to transverse the cell membrane. Due to its toxicity and stability of the structure, saporin has proven extremely useful for construction of immunotoxins.
Product Categories/Family for SAP2 active protein

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
32,811 Da
NCBI Official Full Name
saporin
UniProt Protein Name
Ribosome-inactivating protein saporin-2
UniProt Gene Name
SAP2
UniProt Synonym Gene Names
SAP-2; SO-2
UniProt Entry Name
RIP2_SAPOF

Uniprot Description

Function: Ribosome-inactivating protein of type 1, inhibits protein synthesis in animal cells. Useful as immunotoxin for pharmacological applications.

Catalytic activity: Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.

Sequence similarities: Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.

Similar Products

Product Notes

The Saporin sap2 (Catalog #AAA634857) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Saporin can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA. Researchers should empirically determine the suitability of the Saporin sap2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Saporin, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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