Rabbit anti-Human, Mouse RNF207 Polyclonal Antibody | anti-RNF207 antibody

RNF207, CT (RNF207, C1orf188, RING finger protein 207) (FITC)

Cat. Num. AAA6342800

• Gene Names: RNF207; C1orf188
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: RNF207; Polyclonal Antibody; CT (RNF207; C1orf188; RING finger protein 207) (FITC); RING finger protein 207; anti-RNF207 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-RNF207 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: RNF207 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-555 amino acids from the C-terminal region of human RNF207.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(RNF207 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the RNF207 antibody detected the RNF207 protein (arrow).)

Western Blot (WB)

(RNF207 Antibody (C-term) western blot analysis in mouse Neuro-2a tissue lysates (35ug/lane).This demonstrates the antibody detected the protein (arrow).)

Product Categories/Family for anti-RNF207 antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger

References

Pfeufer, A., et al. Nat. Genet. 41(4):407-414(2009). Newton-Cheh, C., et al. Nat. Genet. 41(4):399-406(2009). Wistow, G., et al. Mol. Vis. 8, 171-184 (2002).

NCBI and Uniprot Product Information

• NCBI GI #: 124487387
• NCBI GeneID: 388591
• NCBI Accession #: NP_997279.2
• NCBI GenBank Nucleotide #: NM_207396.2
• UniProt Accession #: Q6ZRF8; Q5TGS6; Q6ZS63; Q96MP2; A2VCM8; B4DFR6
• Molecular Weight: 70,861 Da
• NCBI Official Full Name: RING finger protein 207
• NCBI Official Synonym Full Names: ring finger protein 207
• NCBI Official Symbol: RNF207
• NCBI Official Synonym Symbols: C1orf188
• NCBI Protein Information: RING finger protein 207
• UniProt Protein Name: RING finger protein 207
• Protein Family: RING finger protein
• UniProt Gene Name: RNF207
• UniProt Synonym Gene Names: C1orf188
• UniProt Entry Name: RN207_HUMAN

Uniprot Description

Polymorphism: Genetic variation in RNF207 may influence the duration of QT interval, a mesure of cardiac repolarization that depends on multiple environmental and genetic contributors. Prolonged or shortened QT intervals predisposes to ventricular arrhythmias and are a risk factor for sudden cardiac death.

Sequence similarities: Contains 1 B box-type zinc finger.Contains 1 RING-type zinc finger.

Sequence caution: The sequence AAI28238.1 differs from that shown. Reason: Erroneous initiation.