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Western Blot (WB) (NAT1 Antibody (center) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the NAT1 antibody detected the NAT1 protein (arrow).)

Rabbit anti-Human NAT1 Polyclonal Antibody | anti-NAT1 antibody

NAT1, ID (NAT1, AAC1, Arylamine N-acetyltransferase 1, Arylamide acetylase 1, Monomorphic arylamine N-acetyltransferase, N-acetyltransferase type 1) (AP)

Gene Names
NAT1; AAC1; MNAT; NATI; NAT-1
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
NAT1; Polyclonal Antibody; ID (NAT1; AAC1; Arylamine N-acetyltransferase 1; Arylamide acetylase 1; Monomorphic arylamine N-acetyltransferase; N-acetyltransferase type 1) (AP); N-acetyltransferase type 1; anti-NAT1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Sequence Length
290
Applicable Applications for anti-NAT1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
NAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-130 amino acids from the Central region of human NAT1.
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(NAT1 Antibody (center) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the NAT1 antibody detected the NAT1 protein (arrow).)

Western Blot (WB) (NAT1 Antibody (center) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the NAT1 antibody detected the NAT1 protein (arrow).)
Related Product Information for anti-NAT1 antibody
This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human geneome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-NAT1 antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010): Minchin, R.F., et al. Int. J. Biochem. Cell Biol. 39(11):1999-2005(2007). Barker, D.F., et al. Pharmacogenet. Genomics 16(7):515-525(2006). Boukouvala, S., et al. Basic Clin. Pharmacol. Toxicol. 96(5):343-351(2005).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
9
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
arylamine N-acetyltransferase 1 isoform a
NCBI Official Synonym Full Names
N-acetyltransferase 1
NCBI Official Symbol
NAT1
NCBI Official Synonym Symbols
AAC1; MNAT; NATI; NAT-1
NCBI Protein Information
arylamine N-acetyltransferase 1
UniProt Protein Name
Arylamine N-acetyltransferase 1
UniProt Gene Name
NAT1
UniProt Synonym Gene Names
AAC1; MNAT; NAT-1
UniProt Entry Name
ARY1_HUMAN

NCBI Description

This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Uniprot Description

NAT1: Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. Belongs to the arylamine N-acetyltransferase family.

Protein type: Xenobiotic Metabolism - drug metabolism - other enzymes; Acetyltransferase; Secondary Metabolites Metabolism - caffeine; EC 2.3.1.5

Chromosomal Location of Human Ortholog: 8p22

Cellular Component: cytosol

Molecular Function: arylamine N-acetyltransferase activity

Biological Process: xenobiotic metabolic process

Research Articles on NAT1

Similar Products

Product Notes

The NAT1 nat1 (Catalog #AAA6323880) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NAT1, ID (NAT1, AAC1, Arylamine N-acetyltransferase 1, Arylamide acetylase 1, Monomorphic arylamine N-acetyltransferase, N-acetyltransferase type 1) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NAT1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the NAT1 nat1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NAT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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