Rabbit anti-Human, Mouse Kcnj11 Polyclonal Antibody | anti-Kcnj11 antibody

Kcnj11, NT (Kcnj11, ATP-sensitive inward rectifier potassium channel 11, Inward rectifier K(+) channel Kir6.2, Potassium channel, inwardly rectifying subfamily J member 11) (Biotin)

Cat. Num. AAA6312513

• Gene Names: Kcnj11; mBIR; Kir6.2
• Reactivity: Human, Mouse
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: Kcnj11; Polyclonal Antibody; NT (Kcnj11; ATP-sensitive inward rectifier potassium channel 11; Inward rectifier K(+) channel Kir6.2; Potassium channel; inwardly rectifying subfamily J member 11) (Biotin); inwardly rectifying subfamily J member 11; anti-Kcnj11 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-Kcnj11 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: Mouse Kcnj11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Kcnj11.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Mouse Kcnj11 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the Mouse Kcnj11 antibody detected the Mouse Kcnj11 protein (arrow).)

Western Blot (WB)

(Mouse Kcnj11 Antibody (N-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the Mouse Kcnj11 antibody detected the Mouse Kcnj11 protein (arrow).)

Related Product Information for anti-Kcnj11 antibody

This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium (By similarity).

Product Categories/Family for anti-Kcnj11 antibody

Antibodies; Ion Channel

References

Hugill, A., et al. Diabetologia 53(11):2352-2356(2010). Li, J., et al. J. Biol. Chem. 285(37):28723-28730(2010). Marhfour, I., et al. Cell Tissue Res. 340(2):335-346(2010). Kurata, H.T., et al. PLoS Biol. 8 (2), E1000315 (2010): Alekseev, A.E., et al. Cell Metab. 11(1):58-69(2010).

NCBI and Uniprot Product Information

• NCBI GI #: 6754426
• NCBI GeneID: 16514
• NCBI Accession #: NP_034732.1
• NCBI GenBank Nucleotide #: NM_010602.3
• UniProt Accession #: Q61743; Q9QX21
• Molecular Weight: 43,562 Da
• NCBI Official Full Name: ATP-sensitive inward rectifier potassium channel 11 isoform 1
• NCBI Official Synonym Full Names: potassium inwardly rectifying channel, subfamily J, member 11
• NCBI Official Symbol: Kcnj11
• NCBI Official Synonym Symbols: mBIR; Kir6.2
• NCBI Protein Information: ATP-sensitive inward rectifier potassium channel 11
• UniProt Protein Name: ATP-sensitive inward rectifier potassium channel 11
• Protein Family: ATP-sensitive inward rectifier potassium channel
• UniProt Gene Name: Kcnj11
• UniProt Entry Name: KCJ11_MOUSE