Rabbit anti-Human K2C78 Polyclonal Antibody | anti-K2C78 antibody

K2C78, ID (KRT78, K5B, KB40, Keratin, type II cytoskeletal 78, Cytokeratin-78, Keratin-5b, Keratin-78, Type-II keratin Kb40) (APC)

Cat. Num. AAA6311973

• Gene Names: KRT78; K5B; K78; Kb40; CK-78
• Reactivity: Human
• Applications: Flow Cytometry, Functional Assay, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: K2C78; Polyclonal Antibody; ID (KRT78; K5B; KB40; Keratin; type II cytoskeletal 78; Cytokeratin-78; Keratin-5b; Keratin-78; Type-II keratin Kb40) (APC); KRT78; Type-II keratin Kb40; anti-K2C78 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-K2C78 antibody: Flow Cytometry (FC/FACS), FLISA, Western Blot (WB)
• Application Notes: FC/FACS: 1:10-50; FLISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: K2C78 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182~212 amino acids from the Central region of human K2C78.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of K2C78 Antibody (Center) in Hela cell line lysates (35ug/lane). K2C78 (arrow) was detected using the purified Pab.)

Flow Cytometry (FC/FACS)

(K2C78 Antibody (Center) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Related Product Information for anti-K2C78 antibody

This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.

Product Categories/Family for anti-K2C78 antibody

Antibodies; Cytokeratin

References

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007). Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006). Rogers, M.A., et al. J. Invest. Dermatol. 124(3):536-544(2005). Hesse, M., et al. Eur. J. Cell Biol. 83(1):19-26(2004). Coulombe, P.A., et al. Curr. Opin. Cell Biol. 14(1):110-122(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 89357932
• NCBI GeneID: 196374
• NCBI Accession #: NP_775487.2
• NCBI GenBank Nucleotide #: NM_173352.3
• UniProt Accession #: Q8N1N4; Q5HYM7; Q7RTT2; A8K4D6
• Molecular Weight: 56,866 Da
• NCBI Official Full Name: keratin, type II cytoskeletal 78 isoform 1
• NCBI Official Synonym Full Names: keratin 78
• NCBI Official Symbol: KRT78
• NCBI Official Synonym Symbols: K5B; K78; Kb40; CK-78
• NCBI Protein Information: keratin, type II cytoskeletal 78; keratin-5b; cytokeratin-78; type-II keratin Kb40
• UniProt Protein Name: Keratin, type II cytoskeletal 78
• UniProt Gene Name: KRT78
• UniProt Synonym Gene Names: K5B; KB40; CK-78; K78
• UniProt Entry Name: K2C78_HUMAN