NDUFS7 Antibody | anti-NDUFS7 antibody

NDUFS7 Antibody

Cat. Num. AAA8509883

• Gene Names: NDUFS7; PSST; CI-20; MY017; CI-20KD
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: NDUFS7; NDUFS7 Antibody; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7; mitochondrial; EC 1.6.5.3; EC 1.6.99.3; NADH-ubiquinone oxidoreductase 20 kDa subunit; Complex I-20kD; CI-20kD; PSST subunit; anti-NDUFS7 antibody

• Reactivity: Human, Mouse, Rat
• Specificity: NDUFS7 antibody detects endogenous levels of total NDUFS7 protein.
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 213

• Applicable Applications for anti-NDUFS7 antibody: Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: IHC: 1:50-1:100; ELISA: 1:40000
• Immunogen: The antiserum was produced against synthesized peptide derived from internal of human NDUFS7.
• Preparation and Storage: Store at-20 degree C for 1 year.

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using NDUFS7 antibody.)

References

Hyslop S.J., Genomics 37:375-380(1996). Grimwood J., Nature 428:529-535(2004). The MGC Project Team; Genome Res. 14:2121-2127(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 187281616
• NCBI GeneID: 374291
• NCBI Accession #: NP_077718.3
• NCBI GenBank Nucleotide #: NM_024407.4
• UniProt Accession #: O75251; Q2T9H7; Q9BV17; B3KRI2
• Molecular Weight: 22,203 Da
• NCBI Official Full Name: NADH dehydrogenase
• NCBI Official Synonym Full Names: NADH:ubiquinone oxidoreductase core subunit S7
• NCBI Official Symbol: NDUFS7
• NCBI Official Synonym Symbols: PSST; CI-20; MY017; CI-20KD
• NCBI Protein Information: NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
• UniProt Protein Name: NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
• Protein Family: NADH dehydrogenase [ubiquinone] iron-sulfur protein
• UniProt Gene Name: NDUFS7
• UniProt Synonym Gene Names: CI-20kD

NCBI Description

This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions. [provided by RefSeq, Jul 2008]

Uniprot Description

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.