Rabbit anti-Human CSRNP2 Polyclonal Antibody | anti-CSRNP2 antibody

CSRNP2, CT (CSRNP2, C12orf22, FAM130A1, TAIP12, Cysteine/serine-rich nuclear protein 2, Protein FAM130A1, TGF-beta-induced apoptosis protein 12) (MaxLight 490)

Cat. Num. AAA6289435

• Gene Names: CSRNP2; C12orf2; PPP1R72; TAIP-12; C12orf22; FAM130A1
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CSRNP2; Polyclonal Antibody; CT (CSRNP2; C12orf22; FAM130A1; TAIP12; Cysteine/serine-rich nuclear protein 2; Protein FAM130A1; TGF-beta-induced apoptosis protein 12) (MaxLight 490); TGF-beta-induced apoptosis protein 12; anti-CSRNP2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.

• Applicable Applications for anti-CSRNP2 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: CSRNP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-538 amino acids from the C-terminal region of human CSRNP2.
• Conjugate: MaxLight490
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Related Product Information for anti-CSRNP2 antibody

CSRNP2 binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity (By similarity). May play a role in apoptosis.

Product Categories/Family for anti-CSRNP2 antibody

Antibodies; Apoptosis

References

Gingras, S., et al. PLoS ONE 2 (8), E808 (2007): Colland, F., et al. Genome Res. 14(7):1324-1332(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 13540602
• NCBI GeneID: 81566
• NCBI Accession #: NP_110436.1
• NCBI GenBank Nucleotide #: NM_030809.2
• UniProt Accession #: Q9H175
• Molecular Weight: 59,591 Da
• NCBI Official Full Name: cysteine/serine-rich nuclear protein 2
• NCBI Official Synonym Full Names: cysteine-serine-rich nuclear protein 2
• NCBI Official Symbol: CSRNP2
• NCBI Official Synonym Symbols: C12orf2; PPP1R72; TAIP-12; C12orf22; FAM130A1
• NCBI Protein Information: cysteine/serine-rich nuclear protein 2; CSRNP-2; TGF-beta-induced apoptosis protein 12; protein phosphatase 1, regulatory subunit 72; family with sequence similarity 130, member A1
• UniProt Protein Name: Cysteine/serine-rich nuclear protein 2
• Protein Family: Cysteine/serine-rich nuclear protein
• UniProt Gene Name: CSRNP2
• UniProt Synonym Gene Names: C12orf22; FAM130A1; TAIP12; CSRNP-2; TAIP-12
• UniProt Entry Name: CSRN2_HUMAN

NCBI Description

The protein encoded by this gene belongs to the CSRNP family of nuclear proteins that share conserved regions, including cysteine- and serine- rich regions, a basic domain, a transcriptional activation domain, and bind the sequence 'AGAGTG', thus have the hallmark of transcription factors. Studies in mice suggest that these genes may have redundant functions. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]

Uniprot Description

TAIP12: Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. May play a role in apoptosis. Belongs to the AXUD1 family.

Chromosomal Location of Human Ortholog: 12q13.11-q13.12

Cellular Component: nucleus

Molecular Function: protein binding; sequence-specific DNA binding; transcription factor activity; phosphatase binding

Biological Process: transcription, DNA-dependent; apoptosis; positive regulation of transcription from RNA polymerase II promoter