Rabbit anti-Human ARHGEF18 Polyclonal Antibody | anti-ARHGEF18 antibody
ARHGEF18, NT (ARHGEF18, KIAA0521, Rho guanine nucleotide exchange factor 18, 114kD Rho-specific guanine nucleotide exchange factor, Septin-associated RhoGEF) (MaxLight 490)
Gene Names
ARHGEF18; P114-RhoGEF
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
ARHGEF18; Polyclonal Antibody; NT (ARHGEF18; KIAA0521; Rho guanine nucleotide exchange factor 18; 114kD Rho-specific guanine nucleotide exchange factor; Septin-associated RhoGEF) (MaxLight 490); Septin-associated RhoGEF; anti-ARHGEF18 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Applicable Applications for anti-ARHGEF18 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
ARHGEF18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the N-terminal region of human ARHGEF18.
Conjugate
MaxLight490
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Related Product Information for anti-ARHGEF18 antibody
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified.
Product Categories/Family for anti-ARHGEF18 antibody
References
Ichikawa, S., et al. J. Bone Miner. Res. 25(8):1821-1829(2010). Niu, J., et al. Circ. Res. 93(9):848-856(2003). Rabizadeh, S., et al. Cytokine Growth Factor Rev. 14 (3-4), 225-239 (2003): Salehi, A.H., et al. J. Biol. Chem. 277(50):48043-48050(2002). Harrington, A.W., et al. J. Neurosci. 22(1):156-166(2002).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
114,077 Da
NCBI Official Full Name
rho guanine nucleotide exchange factor 18 isoform a
NCBI Official Synonym Full Names
Rho/Rac guanine nucleotide exchange factor 18
NCBI Official Symbol
ARHGEF18
NCBI Official Synonym Symbols
P114-RhoGEF
NCBI Protein Information
rho guanine nucleotide exchange factor 18
UniProt Protein Name
Rho guanine nucleotide exchange factor 18
Protein Family
UniProt Gene Name
ARHGEF18
UniProt Synonym Gene Names
KIAA0521; p114-Rho-GEF; p114RhoGEF; SA-RhoGEF
UniProt Entry Name
ARHGI_HUMAN
NCBI Description
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
Research Articles on ARHGEF18
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Product Notes
The ARHGEF18 arhgef18 (Catalog #AAA6274979) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARHGEF18, NT (ARHGEF18, KIAA0521, Rho guanine nucleotide exchange factor 18, 114kD Rho-specific guanine nucleotide exchange factor, Septin-associated RhoGEF) (MaxLight 490) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ARHGEF18 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ARHGEF18 arhgef18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARHGEF18, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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