Mouse anti-Human CD142 Monoclonal Antibody | anti-CD142 antibody
CD142 (CD142 Antigen, Coagulation Factor III, F3, Tissue Factor, TF, TFA, Thromboplastin) (FITC)
Reactivity
Human
Applications
ELISA, Flow Cytometry, Functional Assay, Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Purified by protein G affinity chromatography from ascites.
Synonyms
CD142; Monoclonal Antibody; CD142 (CD142 Antigen; Coagulation Factor III; F3; Tissue Factor; TF; TFA; Thromboplastin) (FITC); anti-CD142 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
10B757
Specificity
Recognizes human CD142. Recognizes an epitope within the extracellular domain, epitope locus I. Recognizes both the reduced and native non-reduced human and primate tissue factors. It does not inhibit coagulation or neutralize factot VII binding to CD142. Species Crossreactivity: Primate. Does not react with rabbit.
Purity/Purification
Purified by protein G affinity chromatography from ascites.
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Fluorescein isothiocyanate (FITC).
Applicable Applications for anti-CD142 antibody
ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Immunogen
Denatured Tissue factor isolated from human brain by the Factor VII affinity method.
Conjugate
FITC
Preparation and Storage
Store at -20 degree C.
Product Categories/Family for anti-CD142 antibody
References
1. Morrissey, J. H. et al. (1988) Monoclonal antibody analysis of purified and cell-associated tissue factor. Thromb. Res. 52: 247-261, 2. Contrino, J. et al. (1994) In situ characterization of antigenic and functional tissue factor expression in human tumors utilizing monoclonal antibodies and recombinant factor VIIa as probes. Am. J. Path. 145: 1315-1322. 3. Drake, T. A. et al. (1989) Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis. Am. J. Pathol. 134: 1087-1097, 4. Stearns-Kurosawa, D. J. et al. (2006) Sepsis and pathophysiology of anthrax in a nonhuman primate model. Am. J. Pathol. 169: 433-444, 5. Mueller, B. M. et al. (1992) Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis. Proc. Natl. Acad. Sci. U. S. A. 89: 11832-11836.
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Product Notes
The CD142 (Catalog #AAA6249508) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD142 (CD142 Antigen, Coagulation Factor III, F3, Tissue Factor, TF, TFA, Thromboplastin) (FITC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD142 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the CD142 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD142, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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