Rabbit HEY 1, HRT1, aa207-220 Polyclonal Antibody | anti-Hey1 antibody
HEY 1, HRT1, aa207-220 (Helix-loop-helix Transcription Factor)
Purified by affinity chromatography.
Purified by affinity chromatography.
Dilution: Western Blot: 1:200-1:1000 (ECL)
Immunohistochemistry (Frozen sections): 1:200-1:1000; Not tested for paraffin.
NCBI and Uniprot Product Information
Uniprot Description
HEY1: Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'- CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6. Belongs to the HEY family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear receptor co-regulator; Transcription factor
Cellular Component: cytoplasm; nucleus
Molecular Function: protein dimerization activity; protein binding; DNA binding; sequence-specific DNA binding; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; blood vessel development; Notch signaling pathway; transcription, DNA-dependent; multicellular organismal development; negative regulation of transcription from RNA polymerase II promoter; osteoblast development; positive regulation of osteoblast differentiation; negative regulation of neuron differentiation; regulation of transcription, DNA-dependent; negative regulation of Notch signaling pathway; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; vasculogenesis; anterior/posterior axis specification; mesenchymal cell development
Research Articles on Hey1
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Product Notes
The Hey1 hey1 (Catalog #AAA623537) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HEY 1, HRT1, aa207-220 (Helix-loop-helix Transcription Factor) reacts with Human, Rodent and may cross-react with other species as described in the data sheet. AAA Biotech's HEY 1, HRT1, aa207-220 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot and Immunohistochemistry. Dilution: Western Blot: 1:200-1:1000 (ECL) Immunohistochemistry (Frozen sections): 1:200-1:1000; Not tested for paraffin. Researchers should empirically determine the suitability of the Hey1 hey1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HEY 1, HRT1, aa207-220, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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